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Energy Metabolism in Cardiac Remodeling and Heart Failure
(2013-05-01)
Fatty acids are the main substrates used by mitochondria to provide myocardial energy under normal conditions. During heart remodeling, however, the fuel preference switches to glucose. In the earlier stages of cardiac ...
Sympathetic overactivity precedes metabolic dysfunction in a fructose model of glucose intolerance in mice
(AMER PHYSIOLOGICAL SOCBETHESDA, 2012)
De Angelis K, Senador DD, Mostarda C, Irigoyen MC, Morris M. Sympathetic overactivity precedes metabolic dysfunction in a fructose model of glucose intolerance in mice. Am J Physiol Regul Integr Comp Physiol 302: R950-R957, ...
Brazilian Curcuma longa L. attenuates comorbidities by modulating adipose tissue dysfunction in obese rats
(2018-12-01)
Background: Adipose tissue dysfunction is a condition characterized by inflammation and oxidative stress able to lead metabolic disorders. Curcuma longa L. (Cl) is a rhizome commonly used in Indian culinary which presents ...
Neutrophil dysfunction varies with the stage of canine visceral leishmaniosis
(2013-09-01)
Canine visceral leishmaniosis (CVL) causes a dependent-stage alteration in neutrophil oxidative metabolism. When production of reactive oxygen species (ROS) exceeds the antioxidant capacity of neutrophils, apoptosis is ...
Insulin-like growth factor-1 deficiency and metabolic syndrome
(Open Access Publisher, 2016)
Mitochondrial dysfunction affects chloroplast functions
(Landes Bioscience, 2011)
The transcriptomic response of A9:u-ATP9 and apetala3:u-ATP9 lines carrying a mitochondrial dysfunction in flower tissues has been characterized. Both lines showed an alteration in the transcription of several genes involved ...
Chronic glucocorticoid-rich milieu and liver dysfunction
(Hindaw Publishing Corporation, 2016-09)
We investigated the impact of chronic hypercorticosteronemia (due to neonatal monosodium L-glutamate, MSG, and treatment) on liver oxidative stress (OS), inflammation, and carbohydrate/lipid metabolism in adult male rats. ...
White Adipose Tissue and Circadian Rhythm Dysfunctions in Obesity: Pathogenesis and Available Therapies
(Karger, 2017-04)
A combined neuroendocrine, metabolic, and chronobiological view can help to better understand the multiple and complex mechanisms involved in obesity development and maintenance, as well as to provide new effective approaches ...