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Bile Acids and Nonalcoholic Fatty Liver Disease: Molecular Insights and Therapeutic Perspectives
(2017)
Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem worldwide and an important risk factor for both hepatic and cardiometabolic mortality. The rapidly increasing prevalence of this disease and of its ...
Combined administration of docosahexaenoic acid and thyroid hormone synergistically enhances rat liver levels of resolvins RvD1 and RvD2
(2019)
Supplementation with omega-3 fatty acids or thyroid hormone (T-3) exhibit negative effects on inflammatory reactions in experimental animals. The aim of this work was to assess the hypothesis that docosahexaenoic acid (DHA) ...
The acute-phase response of the liver in relation to thyroid hormone-induced redox signaling
(ELSEVIER, 2006-05-01)
Recently, we reported that 3,3,5-triiodothyronine (T-3) induces the expression of redox-sensitive genes as a nongenomic mechanism of T3 action. In this study, we show that T3 administration to rats (daily doses of 0. 1 ...
Combined administration of docosahexaenoic acid and thyroid hormone synergistically enhances rat liver levels of resolvins RvD1 and RvD2
(Churchill Livingstone, 2019)
© 2018 Supplementation with omega-3 fatty acids or thyroid hormone (T3) exhibit negative effects on inflammatory reactions in experimental animals. The aim of this work was to assess the hypothesis that docosahexaenoic ...
Redox-dependent effects in the physiopathological role of bile acids
(Hindawi, 2021)
Bile acids (BA) are recognized by their role in nutrient absorption. However, there is growing evidence that BA also have endocrine and metabolic functions. Besides, the steroidal-derived structure gives BA a toxic potential ...
Metabolic basis for thyroid hormone liver preconditioning: Upregulation of AMP-activated protein kinase signaling
(2012)
The liver is a major organ responsible for most functions of cellular metabolism and a mediator between dietary and endogenous sources of energy for extrahepatic tissues. In this context, adenosine-monophosphate- (AMP-) ...
Inflammatory myofibroblastic tumor of the stomach: an unusual complication after gastrectomy
(MOSBY, 2006-02)
Inflammatory myofibroblastic tumor (IMT) is a benign lesion
that was first described in the liver by Pack and Baker in
1953.1 It is a rare lesion that has been described in many
organs and tissues of children and young ...
Effects of selective bile duct ligation on liver parenchyma in young animals: histologic and molecular evaluations
(W B SAUNDERS CO-ELSEVIER INCPHILADELPHIA, 2012)
Background/Purpose: The mechanisms of increased collagen production and liver parenchyma fibrosis are poorly understood. These phenomena are observed mainly in children with biliary obstruction (BO), and in a great number ...
Redox signaling associated with thyroid hormone action: perspectives in medical sciences
(2016)
Redox signaling, as a consequence of thyroid hormone (TH)-induced energy metabolism, triggers adaptive cellular changes to resume homeostasis. In the liver, this is associated with the activation of redox-sensitive ...