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Crosstalk between ROS-dependent apoptotic and autophagic signaling pathways in Zn(II) phthalocyanine photodynamic therapy of melanoma
(Elsevier Science Inc, 2020-01-01)
Melanoma is the most aggressive type of skin cancer, highly resistant to conventional therapies. Photodynamic therapy (PDT) is a minimally invasive treatment modality that combines the use of a photosensitizer, visible ...
The heterotrimeric G-protein complex modulates light sensitivity in arabidopsis thaliana seed germination
(Wiley Blackwell Publishing, Inc, 2009-07)
Release of dormancy and induction of seed germination are complex traits finely regulated by hormonal signals and environmental cues such as temperature and light. The Red (R):Far-Red (FR) phytochrome photoreceptors mediate ...
SLAM and CD31: signaling molecules involved in cytokine secretion during the development of innate and adaptive immune responses
(Elsevier, 2007-02)
Immune cells are modulated through the crosslinking of receptors named “immunoreceptors”. Ligation of immunoreceptors by their ligands induces a tyrosine-phosphorylation signal that is essential for cell activation or ...
Protein kinases in the photic signaling of the mammalian circadian clock
(Yale School of Medicine, 2019-06-27)
Circadian clocks drive biological rhythms in physiology and behavior, providing a selective advantage by enabling organisms to synchronize to the 24 h environmental day. This process depends on lightdark transitions as the ...
Role of G-Substrate in the NO/cGMP/PKG Signal Transduction Pathway for Photic Entrainment of the Hamster Circadian Clock
(SAGE Publications, 2021-01)
The mammalian circadian clock at the hypothalamic suprachiasmatic nuclei (SCN) entrains biological rhythms to the 24- h cyclic environment, by encoding light-dark transitions in SCN neurons. Light pulses induce phase shifts ...
Role of G-substrate in the NO/cGMP/PKG signal transduction pathway for photic entrainment of the hamster circadian clock
(SAGE Publishing, 2021)
Abstract: The mammalian circadian clock at the hypothalamic suprachiasmatic nuclei (SCN) entrains biological rhythms to the 24-
h cyclic environment, by encoding light-dark transitions in SCN neurons. Light pulses induce ...
Biophysical characterization of the recombinant importin-α from neurospora crassa
(2013-02-01)
Neurospora crassa has been widely used as a model organism and contributed to the development of biochemistry and molecular biology by allowing the identification of many metabolic pathways and mechanisms responsible for ...
Biophysical characterization of the recombinant importin-α from neurospora crassa
(2013-02-01)
Neurospora crassa has been widely used as a model organism and contributed to the development of biochemistry and molecular biology by allowing the identification of many metabolic pathways and mechanisms responsible for ...
Nanomedicine associated with photodynamic therapy for glioblastoma treatment
(2017-10-01)
Glioblastoma, also known as glioblastoma multiforme (GBM), is the most recurrent and malignant astrocytic glioma found in adults. Biologically, GBMs are highly aggressive tumors that often show diffuse infiltration of the ...