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Interdependency of regulatory effects of iron and riboflavin in the foodborne pathogen Shigella flexneri determined by integral transcriptomics
(PeerJ, 2020)
Shigella flexneri is the causative agent of dysentery. For pathogens, iron is a critical
micronutrient as its bioavailability is usually low in bacterial niches. This metal is involved in critical physiological processes ...
The Induction of Oxidative/Nitrosative Stress, Inflammation, and Apoptosis by a Ferric Carboxymaltose Copy Compared to Iron Sucrose in a Non-Clinical Model
(Premchand Shantidevi Research Foundation, 2015-12)
Introduction: Ferric carboxymaltose is a next-generation polynuclear iron(III)-hydroxide carbohydrate complex for intravenous iron therapy belonging to the class of so-called non-biological complex drugs. The product ...
Nitric Oxide and Frataxin: Two Players Contributing to Keep Cellular Iron Homeostasis.
(Oxford University Press, 2009-06-25)
BackgroundNitric oxide (NO) is a signalling and physiologically active molecule in animals, plants and bacteria. The specificity of the molecular mechanism(s) involved in transducing the NO signal within and between cells ...
An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells
(2002)
Intracellular reactive iron is a source of free radicals and a possible cause of cell damage. In this study, we analyzed the changes in iron homeostasis generated by iron accumulation in neuroblastoma (N2A) cells and ...
Noxious iron–calcium connections in neurodegeneration
(Frontiers Media, 2019)
Iron and calcium share the common feature of being essential for normal neuronal function. Iron is required for mitochondrial function, synaptic plasticity, and the development of cognitive functions whereas cellular calcium ...
Impacto da inflamação na regulação do ferro e deficiência funcional de ferro
(Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2010-06-01)
Functional iron deficiency can be defined as an imbalance between the iron needs of the erythroid marrow and iron supply. Iron deficiency occurs in the absence of iron deposits, as in the case of iron deficiency anemia ...
IurV, encoded by ORF VCA0231, is involved in the regulation of iron uptake genes in vibrio cholerae
(MDPI, 2020)
The pathogen Vibrio cholerae has multiple iron acquisition systems which allow bacteria to exploit a variety of iron sources across the different environments on which it thrives. The expression of such iron uptake systems ...
Glutathione and ascorbic acid protect Arabidopsis plants against detrimental effects of iron deficiency
(Oxford University Press, 2013-06)
Iron is an essential micronutrient required for a wide variety of cellular functions in plant growth and development. Chlorosis is the first visible symptom in iron-deficient plants. Glutathione (GSH) and ascorbic acid ...
Friction and wear properties of functionally graded aluminum matrix composites
(2003-06-25)
Aluminum matrix composites are currently considered as promising materials for tribological applications in the automotive, aircraft and aerospace industries due to their great advantage of a high strength-to-weight ratio. ...