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Novel LVNC genetic aetiology discovered by an original whole-exome sequencing data combinatory filtering method
Background: Left ventricular non-compaction (LVNC) is a cardiomyopathy characterized by deep intra-trabecular recesses and prominent left ventricular trabeculae. This cardiomyopathy has remarkable phenotypic and genetic ...
Expression Analysis of Wound Healing Genes in Human Periapical Granulomas of Progressive and Stable Nature
(ELSEVIER SCIENCE INCNEW YORK, 2012)
Introduction: Wound healing process involves the activation of extracellular matrix components, remodeling enzymes, cellular adhesion molecules, growth factors, cytokines and chemokines genes. However, the molecular patterns ...
Exposure to bacteriophages t4 and m13 increases integrin gene expression and impairs migration of human pc-3 prostate cancer cells
(2021-10-01)
The interaction between bacteriophages and integrins has been reported in different cancer cell lines, and efforts have been undertaken to understand these interactions in tumor cells along with their possible role in gene ...
The Fibrosis-Targeted Collagen/Integrins Gene Profile Predicts Risk of Metastasis in Pulmonary Neuroendocrine Neoplasms
(2021-08-11)
Recently, collagen/integrin genes have shown promise as predictors of metastasis mainly in non-small cell lung cancer and breast cancer. However, it is unknown if these gene expression profiling differ in metastatic potential ...
Bioactivity effects of extracellular matrix proteins on apical papilla cells
(2021-01-01)
Potent signaling agents stimulate and guide pulp tissue regeneration, especially in endodontic treatment of teeth with incomplete root formation. Objective: This study evaluated the bioactive properties of low concentrations ...
Bioactivity effects of extracellular matrix proteins on apical papilla cells
(Univ Sao Paulo Fac Odontologia Bauru, 2021-01-01)
Potent signaling agents stimulate and guide pulp tissue regeneration, especially in endodontic treatment of teeth with incomplete root formation. Objective: This study evaluated the bioactive properties of low concentrations ...
Síntese e avaliação de biomateriais associados a proteínas da matriz extracelular para a regeneração do tecido pulpar
(Universidade Estadual Paulista (Unesp), 2021-06-30)
A regeneração tecidual guiada tem sido considerada uma estratégia promissora para substituir terapias endodônticas convencionais em casos de dentes com rizogênese incompleta. Portanto, no presente estudo, proteínas da ...
Genomic regions and genes associated with carcass quality in Nelore cattle
(Funpec-editora, 2019-02-26)
Many studies have explored variability to select cattle with high genetic potential for economic interest traits. Genetic variability is a powerful tool to improve production indexes in cattle, as it also is associated ...
Oncogenic potential diverge among human papillomavirus type 16 natural variants
(ACADEMIC PRESS INC ELSEVIER SCIENCESAN DIEGO, 2012)
We compared E6/E7 protein properties of three different HPV-16 variants: AA. E-P and E-350G. Primary human foreskin keratinocytes (PHFK) were transduced with HPV-16 E6 and E7 and evaluated for proliferation and ability to ...
Análise do perfil de expressão gênica pela técnica de microarrays de oligonucleotídeos em subgrupos de pacientes com mieloma múltiplo definidos a partir de antígenos câncer/testículo
(Universidade Federal de São Paulo (UNIFESP), 2008-08-27)
Introducao: Antigenos cancer/testiculo (CT) tem se tornado o grupo de antigenos mais estudados no campo da imunoterapia contra o cancer. Objetivos: Este estudo avaliou a expressao global de 14 CTs em MM para identificar ...