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Prevention of hypertension in patients with pre-hypertension: protocol for the PREVER-prevention trial
(BIOMED CENTRAL LTD, 2011)
Background: Blood pressure (BP) within pre-hypertensive levels confers higher cardiovascular risk and is an intermediate stage for full hypertension, which develops in an annual rate of 7 out of 100 individuals with 40 to ...
Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats
(ELSEVIER IRELAND LTD, 2008)
Altered activity of matrix metalloproteinases (MMPs) is implicated in the vascular remodeling of hypertension. We examined whether increased MMP-2 expression/activity plays a role in the vascular remodeling and dysfunction ...
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension
(SPRINGER, 2011)
The vascular remodeling associated with hypertension involves oxidative stress and enhanced matrix metalloproteinases (MMPs) expression/activity, especially MMP-2. While previous work showed that lercanidipine, a ...
Prenatal malnutrition-induced hypertension in young rats is prevented by neonatal capsaicin treatment
(2002)
Prenatal malnutrition-induced fetal growth retardation in the rat results in elevated arterial blood pressure at adulthood. To test the contribution of cardiovascular sensory C fibers in the hypertensive state, arterial ...
Influence of ovariectomy on cardiac oxidative stress in a renovascular hypertension model
(National Research Council Canada-NRC Research Press, 2012-09)
The aim of this study was to evaluate the potential influence of endogenous ovarian hormones on cardiac oxida-tive stress in renovascular hypertension. Female Wistar rats (N = 10 per group) were divided among 4 groups: (i) ...
Position statement of the Interamerican Society of Cardiology (IASC) on the current guidelines for the prevention, diagnosis and treatment of arterial hypertension 2017–2020
(ElsevierCanadá, 2020-07-15)
Abstract
Objectives
As an Inter-American Society we are convinced of the need to standardize the steps in which we diagnose, evaluate, treat and control hypertension, establishing guidelines and rules that should be ...