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Implications of epigenetic modulation for novel treatment approaches in patients with schizophrenia
(Elsevier B.V., 2014-02-01)
Schizophrenia is a heterogeneous and complex mental disorder with high rates of disability, non-recovery, and relapse. the primary pharmacological treatments for schizophrenia are antipsychotics. Notwithstanding the efficacy ...
Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy
(LIPPINCOTT WILLIAMS & WILKINS, 2014)
Synthesis and pharmacological evaluation of histone deacetylase inhibitors as fetal hemoglobin inducers
(Amer Chemical Soc, 2018-03-18)
The p53 pathway as a molecular target for the suppressive chemopreventive action of the histone deacetylase inhibitor tributyrin in rat hepatocarcinogenesis
(Pergamon-Elsevier B.V. Ltd, 2010-11-01)
Abnormal Methylation of Histone Deacetylase Genes: Implications on Etiology and Epigenetic Therapy of Astrocytomas
(INT INST ANTICANCER RESEARCH, 2011)
Background: A growing body of evidence has revealed, the involvement of epigenetic alterations in the etiology of astrocytomas. In the present study, we aimed to evaluate the association of DNA methylation of histone ...
Low-level laser therapy suppresses the oxidative stress-induced glucocorticoids resistance in U937 cells: Relevance to cytokine secretion and histone deacetylase in alveolar macrophages
(Elsevier B.V., 2014-01-05)
Oxidative stress is present in severe asthma and contributes to the low response to corticoids through the downregulation of histone deacetylase (HDAC) and the increase of cytokines. Low-level laser therapy (LLLT) has been ...