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Testosterona e gonadotrofina coriônica humana estimulam a esteroidogênese em células da granulosa de folículo pré-ovulatório de égua?
(Universidade Federal de Minas Gerais (UFMG), Escola de Veterinária, 2014)
FSH and its second messenger cAMP stimulate the transcription of human anti-müllerian hormone in cultured granulosa cells
(Oxford University Press, 2011-04)
Anti-Müllerian hormone (AMH), also called Müllerian-inhibiting substance, a member of the TGF-β family, is responsible for the regression of Müllerian ducts in the male fetus. In females, AMH is synthesized by granulosa ...
Regulatory role of angiotensin II on progesterone production by cultured human granulosa cells. Expression of angiotensin II type-2 receptor
(1997)
The role of angiotensin II (Angll) in ovarian steroidogenesis is not clearly understood. In order to study its action on progesterone synthesis and to determine which receptor subtype is involved, granulosa cells obtained ...
Concanavalin-A induces granulosa cell death and inhibits fsh-mediated follicular growth and ovarian maturation in female rats
(Endocrine Society, 2013-03-20)
Reproductive success stems from a finely regulated balance between follicular maturation and atresia, in which the role of carbohydrate structure is poorly understood. Here, we describe for the first time a fraction of ...
Expressão do Grb10 durante o crescimento folicular em bovinos
(Universidade Federal de Santa MariaBRMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina Veterinária, 2011-05-05)
The growth factor receptor-bound protein 10 (Grb10) has been extensively studied in human and has been implicated in the regulation of MAPK and PI3K pathways, activated by Insulin-like Growth Factor Receptor (IGF-IR). In ...
In-vitro study of gonadotrophin signaling pathways in human granulosa cells in relation to progesterone receptor expression
(Elsevier, 2017)
In humans, data on gonadotrophin-activated (LH, HCG and FSH) progesterone receptor expression and signalling pathways involved in matrix metalloproteinases (MMPs) expression presumably linked to the follicle rupture, are ...
Metformin has a direct effect on ovarian cells that is dependent on organic cation transporters
(Elsevier Ireland, 2020-01)
Metformin (MET) is the most widely prescribed hypoglycemic drug in type 2 diabetes and Polycystic Ovary Syndrome. Besides its effects on glucose metabolism, MET exerts beneficial effects on these patients? fertility. ...