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The role of the C-terminal region of pulchellin A-chain in the interaction with membrane model systems
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
Pulchellin is a Ribosome Inactivating Protein containing an A-chain (PAC), whose toxic activity requires crossing the endoplasmic reticulum (ER) membrane. In this paper, we investigate the interaction between recombinant ...
The role of the C-terminal region of pulchellin A-chain in the interaction with membrane model systems
(Elsevier B.V., 2012-01-01)
Pulchellin is a Ribosome Inactivating Protein containing an A-chain (PAC), whose toxic activity requires crossing the endoplasmic reticulum (ER) membrane. in this paper, we investigate the interaction between recombinant ...
Brucella abortus MFP: A Trimeric Coiled-Coil Protein with Membrane Fusogenic Activity
(American Chemical Society, 2008-12)
The bacterial genus Brucella consists of a group of facultative intracellular pathogens which produces abortion and infertility in animals and a chronic debilitating febrile illness in humans. BMFP is a basic protein of ...
Interhelical h-bonds modulate the activity of a polytopic transmembrane kinase
(Multidisciplinary Digital Publishing Institute, 2021-07)
DesK is a Histidine Kinase that allows Bacillus subtilis to maintain lipid homeostasis in response to changes in the environment. It is located in the membrane, and has five transmembrane helices and a cytoplasmic catalytic ...
Well-defined regions of the Plasmodium falciparum reticulocyte binding protein homologue 4 mediate interaction with red blood cell membrane
Two widely studied parasite protein families are considered attractive targets for developing a fully effective antimalarial vaccine: the erythrocyte binding antigen (EBA) family defining a sialic acid-dependent invasion ...
A micelle nucleation model for the interaction of dodecyl sulphate with Lys49-phospholipases A(2)
(Elsevier B.V., 2007-01-01)
Bothropstoxin-I (BthTx-I) is a Lys49-PLA(2) from the venom of Bothrops jararacussu that lacks detectable catalytic activity, yet causes rapid Ca2+-independent membrane damage. With the aim of understanding the interaction ...
A micelle nucleation model for the interaction of dodecyl sulphate with Lys49-phospholipases A(2)
(Elsevier B.V., 2007-01-01)
Bothropstoxin-I (BthTx-I) is a Lys49-PLA(2) from the venom of Bothrops jararacussu that lacks detectable catalytic activity, yet causes rapid Ca2+-independent membrane damage. With the aim of understanding the interaction ...
Two disulfide mutants in domain I of Bacillus thuringiensis Cry3Aa δ-endotoxin increase stability with no effect on toxicity
(2012-05)
To increase protein stability and test protein function, three double-cysteine mutations were individually introduced by protein engineering into the cysteinefree Cry3Aa δ-endotoxin from Bacillus thuringiensis.
These ...
Protein engineering of delta-endotoxins of Bacillus thuringiensis
(Pontificia Universidad Católica de Valparaíso, 2004)
caracterización del dominio helicoidal de la subunidad Gas de la proteína G
(1999)
G-proteins (Gajly} tranduce signals to the intracellular milieu by coupling to membrane receptors (GPCR) and to effector systems such as enzymes and ion channels. The Ga subunit Is fonned by a very well conserved domain ...