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Advanced Molecular Surveillance of Hepatitis C Virus
(Mdpi Ag, 2015-03-01)
Hepatitis C virus (HCV) infection is an important public health problem worldwide. HCV exploits complex molecular mechanisms, which result in a high degree of intrahost genetic heterogeneity. This high degree of variability ...
Inter and intrapatient evolution of hepatitis C virus
(Mexican Assoc Hepatology, 2015-07)
Hepatitis C virus (HCV) has a short replication time, high mutation rates and large population sizes, all of which make it an excellent experimental model for evolution studies, because evolution can be visualized in ...
The role of human T cell lymphotrophic virus type 1, hepatitis B virus and hepatitis C virus coinfections in leprosy
(Brasil, 2012)
Leprosy spectrum and outcome is associated with the host immune response against Mycobacterium leprae. The role of coinfections in leprosy patients may be related to a depression of cellular immunity or amplification of ...
In vitro detection of hepatitis C virus in platelets from uninfected individuals exposed to the virus
(Sociedade Brasileira de Medicina Tropical - SBMT, 2013-04-02)
Introduction ,,,,,Despite hepatocytes being the target cells of hepatitis C virus (HCV), viral ribonucleic acid RNA has been detected in other cells, including platelets, which have been described as carriers of the virus ...
In vitro detection of hepatitis C virus in platelets from uninfected individuals exposed to the virus
(Sociedade Brasileira de Medicina Tropical - SBMT, 2013-04-02)
Introduction ,,,,,Despite hepatocytes being the target cells of hepatitis C virus (HCV), viral ribonucleic acid RNA has been detected in other cells, including platelets, which have been described as carriers of the virus ...
Hepatitis C virus molecular evolution: Transmission, disease progression and antiviral therapy
(Baishideng Publishing Group Inc, 2014-11-21)
Hepatitis C virus (HCV) infection represents an important public health problem worldwide. Reduction of HCV morbidity and mortality is a current challenge owned to several viral and host factors. Virus molecular evolution ...
Hepatitis C virus and dental health workers: an update
(Quintessence Publishing Co Inc, 2014-01-01)
Hepatitis C virus (HCV) infection is a worldwide health problem, affecting over 130 million individuals. The virus is transmitted parenterally, making health care professionals a risk group for infection. For this reason ...
Caracterização da estrutura da serino-protease NS3 em pacientes infectados com o vírus da hepatite C do genótipo 3
(Universidade Estadual Paulista (Unesp), 2008-09-15)
A proteína NS3 apresenta dois domínios e é bifuncional. Apresenta três funções enzimáticas que são; 1) atividade de protease; 2) NTPase e 3) helicase. A função protease relaciona-se a tradução da proteína precursora e as ...