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Metabolic profile and genotoxicity in obese rats exposed to cigarette smoke
(2013-08-01)
Objective Experimental studies have shown that exposure to cigarette smoke has negative effects on lipid metabolism and oxidative stress status. Cigarette smoke exposure in nonpregnant and pregnant rats causes significant ...
Metabolic profile and genotoxicity in obese rats exposed to cigarette smoke
(2013-08-01)
Objective Experimental studies have shown that exposure to cigarette smoke has negative effects on lipid metabolism and oxidative stress status. Cigarette smoke exposure in nonpregnant and pregnant rats causes significant ...
Association of polymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease
(WILEY-BLACKWELL PUBLISHING, INC, 2010)
Background and Aims: Although the metabolic risk factors for non-alcoholic fatty liver disease (NAFLD) progression have been recognized, the role of genetic susceptibility remains a field to be explored. The aim of this ...
Estudo do efeito do N-acetil-cisteína através do metabolismo energético, complexos respiratórios e estresse oxidativo no tecido hepático de ratos submetidos ao glutamato monossódico
(Universidade Estadual Paulista (Unesp), 2018-10-31)
A obesidade é considerada um dos maiores problemas de saúde pública em muitos países, uma vez que está associada queda da qualidade de vida. Embora existam vários fatores que corroboram com o desenvolvimento para tal fato, ...
Improvement of metabolic parameters and vascular function by metformin in obese non-diabetic rats
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2013-08-02)
Aims: Metformin is an insulin sensitizing agent with beneficial effects in diabetic patients on glycemic levels and in the cardiovascular system. We examined whether the metabolic changes and the vascular dysfunction in ...
Targeting sentinel proteins and extrasynaptic glutamate receptors: a therapeutic strategy for preventing the effects elicited by perinatal asphyxia?
(Springer, 2018)
Perinatal asphyxia (PA) is a relevant cause of death at the time of labour, and when survival is stabilised, associated with short- and long-term developmental disabilities, requiring inordinate care by health systems and ...
Chronic glucocorticoid-rich milieu and liver dysfunction
(Hindaw Publishing Corporation, 2016-09)
We investigated the impact of chronic hypercorticosteronemia (due to neonatal monosodium L-glutamate, MSG, and treatment) on liver oxidative stress (OS), inflammation, and carbohydrate/lipid metabolism in adult male rats. ...
Mitochondrial permeability transition in neuronal damage promoted by Ca2+ and respiratory chain complex II inhibition
(Blackwell Publishing LtdOxfordInglaterra, 2004)
Heme oxygenase up-regulation under salt stress protects nitrogen metabolism in nodules of soybean plants
(Pergamon-Elsevier Science Ltd, 2008-09)
The behaviour of enzymes involved in nitrogen metabolism, as well as oxidative stress generation and heme oxygenase gene and protein expression and activity, were analysed in soybean (Glycine max L.) nodules exposed to 50, ...