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Mostrando ítems 21-30 de 62
A hepcidina como parâmetro bioquímico na avaliação da anemia por deficiência de ferro
(São Paulo, 2010)
A anemia por deficiência de ferro caracteriza-se como o mais prevalente problema nutricional em todo o mundo. Nesta revisão reuniu-se informações a respeito do metabolismo da hepcidina, avaliando-se seu valor como parâmetro ...
Moléculas que participan en el transporte materno-fetal de hierro: importancia del receptor 1 de transferrina y de la ferroportina en la placenta humanaMolecules implicated in maternal-fetal iron transport across the placental barrier: Role of Transferrin Receptor 1 and Ferroportin
(Universidad de Antioquia, Facultad de MedicinaAlimentación y Nutrición HumanaMedellín, Colombia, 2020)
Non-HFE hemochromatosis
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2012)
Hereditary hemochromatosis (HH) is an autosomal recessive disorder classically related to HFE mutations. However, since 1996, it is known that HFE mutations explain about 80% of HH cases, with the remaining around 20% ...
Cell death induced by mitochondrial complex I inhibition is mediated by Iron Regulatory Protein 1
(Elsevier B.V., 2017)
© 2017 Elsevier B.V. Mitochondrial dysfunction and oxidative damage, often accompanied by elevated intracellular iron levels, are pathophysiological features in a number of neurodegenerative processes. The question arises ...
Antisense gene delivered by an adenoassociated viral vector inhibits iron uptake in human intestinal cells: Potential application in hemochromatosis
(PERGAMON-ELSEVIER SCIENCE LTD, 2005-06-01)
Hereditary hemochromatosis (HH) is a condition in which intestinal iron absorption is greatly elevated. Present treatment is weekly phlebotomy, affecting quality of life and leading to recurrent infections. The iron ...
Effects of acute dietary iron overload in pigs (sus scrofa) with induced type 2 diabetes mellitus
(Springer, 2014)
Epidemiological studies have reported an association
between high iron (Fe) levels and elevated risk of developing
type 2 diabetes mellitus (T2D). It is believed that the
formation of Fe-catalyzed hydroxyl radicals may ...
Hereditary hemochromatosis: An opportunity for gene therapy
(SOCIEDAD BIOLGIA CHILE, 2006)
Levels of body iron should be tightly controlled to prevent the formation of oxygen radicals. lipoperoxidation. genotoxicity, and the production of cytotoxic cytokines, which result in damage to a number of organs. Enterocytes ...