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Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: Control on nuclear factor-κB signaling in consolidation and reconsolidation
(Wiley, 2014-12)
Protein phosphatases are important regulators of neural plasticity and memory. Some studies support that the Ca2+/calmodulin-dependent phosphatase calcineurin (CaN) is, on the one hand, a negative regulator of memory ...
Pre-test metyrapone impairs memory recall in fear conditioning tasks: lack of interaction with I--adrenergic activity
(Frontiers Research Foundation, 2015-03-03)
Cognitive processes, such as learning and memory, are essential for our adaptation to environmental changes and consequently for survival. Numerous studies indicate that hormones secreted during stressful situations, such ...
The lateral neocortex is critical for contextual fear memory reconsolidation
(Nature Publishing Group, 2019-08)
Memories are a product of the concerted activity of many brain areas. Deregulation of consolidation and reprocessing of mnemonic traces that encode fearful experiences might result in fear-related psychopathologies. Here, ...
Contextual, but not auditory, fear conditioning is disrupted by neurotoxic selective lesion of the basal nucleus of amygdala in rats
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2010)
The basolateral amygdala complex (BLA) is involved in acquisition of contextual and auditory fear conditioning. However, the BLA is not a single structure but comprises a group of nuclei, including the lateral (LA), basal ...
Stress influences the dynamics of hippocampal structural remodeling associated with fear memory extinction
(Academic Press Inc Elsevier Science, 2018-11)
Fear extinction is defined as a decline in fear-conditioned responses following non-reinforced exposure to a fear conditioned stimulus, therefore the conditioned stimulus gains new predictive properties. Patients with ...
Flavones from Erythrina falcata are modulators of fear memory
(Biomed Central Ltd, 2014-08-05)
Background: Flavonoids, which have been identified in a variety of plants, have been demonstrated to elicit beneficial effects on memory. Some studies have reported that flavonoids derived from Erythrina plants can provide ...
Lateral Habenula determines long-term storage of aversive memories
(Frontiers, 2014-05)
The Lateral Habenula (LHb) is a small brain structure that codifies negative motivational value and has been related to major depression. It has been shown recently that LHb activation is sufficient to induce aversive ...
Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder
(Humana Press Inc., 2018)