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Candidate gene study reveals DRD1 and DRD2 as putative interacting risk factors for youth depression
(2016-10)
Alterations in the monoaminergic neurotransmission systems are suspected to be involved in the
etiology of neuropsychiatric disorders, including depression. The role of these pathways in the risk of
developing depressive ...
Metabolic syndrome: from the genetics to the pathophysiology
(Springer, 2011-04)
The metabolic syndrome (MS) constitutes a combination of underlying risk factors for an adverse outcome, cardiovascular disease. Thus, the clinical behavior of the MS can be regarded as a whole. Nevertheless, from a ...
Lesch-Nyhan disease in two families from Chiloe island with mutations in the HPRT1 gene
(Taylor & Francis, 2017)
Lesch-Nyhan disease (LND) is a rare X-linked inherited neurogenetic disorder of purine metabolism in which the enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt) is defective. The authors report two independent ...
Pharmacogenomics of Hypertension and Preeclampsia: Focus on Gene-Gene Interactions
(Frontiers Media Sa, 2018-02-28)
Hypertension is a leading cause of cardiovascular mortality, but only about half of patients on antihypertensive therapy achieve blood pressure control. Preeclampsia is defined as pregnancy-induced hypertension and ...
Estimation of statistical power and false discovery rate of QTL mapping methods through computer simulation
(Springer VerlagScience ChinaChinese Academy of SciencesNational Natural Science Foundation of China, 2013)
Generation mean analysis in relation to polygenic systems with epistasis and fixed genes
(Pesquisa Agropecuária Brasileira, 2019)
Epistatic effects on grain yield of soybean [Glycine max (L.) Merrill]Efeitos epistáticos para produção de grãos em soja [Glycine max (L.) Merrill]
(Universidade Federal de Viçosa, 2020)
Use of ridge regression for the prediction of early growth performance in crossbred calves
(Sociedade Brasileira de Genética, 2014)
A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia
(Springer Nature, 2019)
We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions. These include one novel locus for skin pigmentation ...
The cotranscribed Salmonella enterica sv. Typhi Tsx and impX genes encode opposing nucleoside-specific import and export proteins
(Genetics Society of America [Society Publisher] Oxford University Press [University Publisher], 2006-05)
The Salmonella enterica tsx gene encodes a nucleoside-specific outer membrane channel. The Tsx porin is essential for the prototrophic growth of S. enterica sv. Typhi in the absence of nucleosides. RT-PCR analysis shows ...