Buscar
Mostrando ítems 21-30 de 1011
Epigenetic modulations rendering cell-to-cell variability and phenotypic metastability
(Elsevier, 2016-08)
Tumor cells display phenotypic plasticity and heterogeneity due to genetic and epigenetic variations which limit the predictability of therapeutic interventions. Chromatin modifications can arise stochastically but can ...
GFP labelling and epigenetic enzyme expression of bone marrowderived mesenchymal stem cells from bovine foetuses
(Elsevier, 2015)
Mesenchymal stem cells (MSC) are multipotent progenitor cells defined by their ability to self-renew
and give rise to differentiated progeny. Since MSC from adult tissues represent a promising source of cells
for a wide ...
GFP labelling and epigenetic enzyme expression of bone marrow-derived mesenchymal stem cells from bovine foetuses
(Elsevier, 2015)
Mesenchymal stem cells (MSC) are multipotent progenitor cells defined by their ability to self-renew and give rise to differentiated progeny. Since MSC from adult tissues represent a promising source of cells for a wide ...
Epigenetics and autoimmune diseases
(Universidad del Rosario, 2012)
Epigenetics is defined as the study of all inheritable and potentially reversible changes in genome function that do not alter the nucleotide sequence within the DNA. Epigenetic mechanisms such as DNA methylation, histone ...
Polycomb PRC2 complex mediates epigenetic silencing of a critical osteogenic master regulator in the hippocampus
(Elsevier, 2016)
During hippocampal neuron differentiation, the expression of critical inducers of non-neuronal cell lineages must be efficiently silenced. Runx2 transcription factor is the master regulator of mesenchymal cells responsible ...
New insights on epigenetic mechanisms supporting axonal development: Histone marks and miRNAs
(Wiley Blackwell Publishing, Inc, 2020-12)
Mechanisms supporting axon growth and the establishment of neuronal polarity have remained largely disconnected from their genetic and epigenetic fundamentals. Recently, post-transcriptional modifications of histones ...
Insulin resistance and epigenetic regulation: insights from human studies and prospects for future research
(De Gruyter, 2011-12)
In this study, we review the current knowledge and recent insights on the role of epigenetic factors in the development of human insulin resistance (IR)- and metabolic syndrome (MS)-related phenotypes, and attempt to lay ...
P1 epigenetic regulation in leaves of high altitude maize landraces: effect of UV-B radiation
(Frontiers Media, 2021)
The prima donna of epigenetics: the regulation of gene expression by DNA methylation
(Associação Brasileira de Divulgação Científica, 2005)
Epigenetics in Plant Reproductive Development: An Overview from Flowers to Seeds
(2017-01-01)
Plant development is governed by a wide variety of genetic and epigenetic events that regulate cell fate. Flower to seed developmental transition varies greatly between plants and is of importance in research programs ...