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A cholesterol recognition motif in human phospholipid scramblase 1
(Cell Press, 2014-09)
Human phospholipid scramblase 1 (SCR) catalyzes phospholipid transmembrane (flip-flop) motion. This protein is assumed to bind the membrane hydrophobic core through a transmembrane domain (TMD) as well as via covalently ...
Deconstructing the DGAT1 enzyme: Binding sites and substrate interactions
(Elsevier B.V., 2015)
Interaction network and localization of Brucella abortus membrane proteins involved in the synthesis, transport, and succinylation of cyclic β-1,2-glucans
(American Society for Microbiology, 2015-03)
Cyclic β-1,2-glucans (CβG) are periplasmic homopolysaccharides that play an important role in the virulence and interaction of Brucella with the host. Once synthesized in the cytoplasm by the CβG synthase (Cgs), CβG are ...
Effect of partitioning equilibria on the activity of β-galactosidase in heterogeneous media
(Elsevier Science, 2005-12-01)
We had demonstrated that membrane adsorption or penetration differentially modulated β-Galactosidase (β-Gal) activity against soluble substrates (Coll. and Surf., 24, 21, 2002). In a heterogeneous media, not only the enzyme ...
Diacylglycerol regulates the plasma membrane calcium pump from human erythrocytes by direct interaction
(Archives of Biochemistry and Biophysics, 2013)
N-Terminal microdomain peptide from human dihydroorotate dehydrogenase: structure and model membrane interactions
(2014)
The N-terminus of the human dihydroorotate dehydrogenase (HsDHODH) has been described as important for the enzyme attachment in the inner mitochondrial membrane and possibly to regulate enzymatic activity. In this study, ...
Purification and partial characterization of an aminopeptidase from the midgut tissue of Dysdercus peruvianus
(ELSEVIER SCIENCE INC, 2011)
The surface of midgut cells in Hemiptera is ensheathed by a lipoprotein membrane (the perimicrovillar membrane), which delimits a closed compartment with the microvillar membrane, the so-called perimicrovillar space. In ...
Changes of enzyme activity in lipid signaling pathways related to substrate reordering
(BIOPHYSICAL SOCIETY, 2005-08)
The static fluid mosaic model of biological membranes has been progressively complemented by a dynamic membrane model that includes phospholipid reordering in domains that are proposed to extend from nanometers to microns. ...
Kinetics of Na+, K+-ATPase inhibition by an endogenous modulator (II- A)
(Springer/Plenum Publishers, 2000-02)
We have previously reported the isolation by gel filtration and anionic exchange HPLC of two brain Na+, K+-ATPase inhibitors, II-A and II-E, and kinetics of enzyme interaction with the latter. In the present study we ...
2,2'azo-bis-amidinopropane as a radical source for lipid peroxidation and enzyme inactivation studies
(Informa Healthcare, 1991)
1. 2,2'Azo-bis-amidinopropane (ABAP) thermal decomposition produces free radicals that initiate the lipid peroxidation of erythrocyte ghost membranes. 2. Addition of 6-n-propyl-2-thiouracil decreases the rate of the process, ...