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Mutational analyses of human eIF5A-1-identification of amino acid residues critical for eIF5A activity and hypusine modification
(Blackwell Publishing, 2008-01-01)
The eukaryotic translation initiation factor 5A (eIF5A) is the only protein that contains hypusine [N-epsilon-(4-amino-2-hydroxybutyl)lysine], which is required for its activity. Hypusine is formed by post-translational ...
Mutational analyses of human eIF5A-1-identification of amino acid residues critical for eIF5A activity and hypusine modification
(Blackwell Publishing, 2008-01-01)
The eukaryotic translation initiation factor 5A (eIF5A) is the only protein that contains hypusine [N-epsilon-(4-amino-2-hydroxybutyl)lysine], which is required for its activity. Hypusine is formed by post-translational ...
Is there a role for eIF5A in translation?
(Springer, 2007-08-01)
The putative translation factor eIF5A is essential for cell viability and is highly conserved from archaebacteria to mammals. This factor is the only cellular protein that undergoes an essential posttranslational modification ...
eIF5A interacts functionally with eEF2
(Springer, 2012-02-01)
eIF5A is highly conserved from archaea to mammals, essential for cell viability and the only protein known to contain the essential amino acid residue hypusine, generated by a unique posttranslational modification. eIF5A ...
eIF5A interacts functionally with eEF2
(Springer, 2012-02-01)
eIF5A is highly conserved from archaea to mammals, essential for cell viability and the only protein known to contain the essential amino acid residue hypusine, generated by a unique posttranslational modification. eIF5A ...
Participation of eIF4F complex in Junin virus infection: blockage of eIF4E does not impair virus replication
(Wiley, 2013-10)
Translation efficiency of viral mRNAs is a key factor defining both cytopathogenicity and virulence of viruses, which are entirely dependent on the cellular translation machinery to synthesize their proteins. This dependence ...
Estudo da relação entre o fator de início de tradução de eucariotos 5A (eIF5A) e a etapa de elongação da tradução
(Universidade Estadual Paulista (UNESP), 2015)
Estudo das interações de eIF5A com a maquinaria de tradução e com o complexo Ribosome Quality Control, utilizando modelo de Saccharomyces cerevisiae
(Universidade Estadual Paulista (UNESP), 2016)
Functional significance of eIF5A and its hypusine modification in eukaryotes
(Springer, 2010-02-01)
The unusual basic amino acid, hypusine [N(epsilon)-(4-amino-2-hydroxybutyl)-lysine], is a modified lysine with the addition of the 4-aminobutyl moiety from the polyamine spermidine. This naturally occurring amino acid is ...
Functional significance of eIF5A and its hypusine modification in eukaryotes
(Springer, 2010-02-01)
The unusual basic amino acid, hypusine [N(epsilon)-(4-amino-2-hydroxybutyl)-lysine], is a modified lysine with the addition of the 4-aminobutyl moiety from the polyamine spermidine. This naturally occurring amino acid is ...