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Mucoadhesive drug delivery systems
(Universidade de São Paulo (USP), Conjunto Quimicas, 2010-01-01)
Drug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the absorption tissue, the mucous membrane, releasing, the drug at the action ...
Polyacrylic acid polymers hydrogels intended to topical drug delivery: preparation and characterization
(Informa Healthcare, 2015-06-01)
Context: Bioadhesiviness of polyacrylic acid polymers make them promising hydrogels to design topical drug delivery systems, allowing a close contact with biological substrate as well as an enhanced local concentration ...
Stimuli-responsive polymersomes for drug delivery applications
(Elsevier, 2019)
There is a considerable research interest in polymers for drug delivery systems in the medical and pharmaceutical field. Several polymeric materials have been investigated in the development of nanostructures for drug ...
Composite polymer-bioceramic scaffolds with drug delivery capability for bone tissue engineering
(Informa Healthcare, 2013-10)
Next-generation scaffolds for bone tissue engineering (BTE) should exhibit the appropriate combination of mechanical support and morphological guidance for cell proliferation and attachment while at the same time serving ...
Estratégias biotecnológicas para a liberação controlada de antígenos e adjuvantes em vacinas através de lipossomas
(2006-10-01)
Liposomes (LP) are colloidal systems with ability to compartmentalize therapeutic molecules in order to improve biological activity, decreases the potential toxicity, and to obtain prolonged effect. In this work it was ...
Estratégias biotecnológicas para a liberação controlada de antígenos e adjuvantes em vacinas através de lipossomas
(2006-10-01)
Liposomes (LP) are colloidal systems with ability to compartmentalize therapeutic molecules in order to improve biological activity, decreases the potential toxicity, and to obtain prolonged effect. In this work it was ...
Encapsulação da rifampicina em matrizes poliméricas flutuantes obtidas por liofilização a partir de metilcelulose e ftalato de hidroxipropilmetilcelulose. Avaliação da liberação in vitro
(2001-12-01)
Floating multiparticles for oral administration with different compositions were studied from a matricial polymeric system to obtain sustained release. The polymers used in the multiparticles constitution were methylceullose ...
Highlighting the impact of chitosan on the development of gastroretentive drug delivery systems
(2020-09-15)
The development of gastroretentive systems have been growing lately due to the high demand for carriers that increase drug bioavailability and therapeutic effectiveness after oral administration. Most of systems reported ...
Highlights in endocytosis of nanostructured systems
(2017-06-01)
The focus of this review is the cellular internalisation mechanism of nanostructured systems (NSs) and their endosomal escape for targeted drug delivery. Endocytosis is a cellular process of internalisation of different ...