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Acute Regulation of the Arousal-Enhancing Drugs Caffeine and Modafinil on Class IIa HDACs In Vivo and In Vitro: Focus on HDAC7
(Springer, 2020-05)
Psychostimulant drugs, such as modafinil and caffeine, induce transcriptional alterations through the dysregulation of epigenetic mechanisms. We have previously demonstrated that acute modafinil administration is accompanied ...
Individual Differences In Amphetamine Sensitization: Role Of Dorsolateral StriatumDiferencias individuales en la sensibilización a anfetamina: Rol del estriado dorsolateral
(2020)
Clinical evidence shows that the development of drug addiction is not observed in all subjects. While differential changes in nucleus accumbens have been observed, is unknown whether modifications in other basal ganglia ...
The indirect amygdala-dorsal striatum pathway mediates conditioned freezing: Insights on emotional memory networks
(Elsevier B.V., 2008-04-22)
The dorsal striatum (DS) is involved in various forms of learning and memory such as procedural learning, habit learning, reward-association and emotional learning. We have previously reported that bilateral DS lesions ...
Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
(Nature Publishing Group, 2020-04)
Action control is a key brain function determining the survival of animals in their environment. In mammals, neurons expressing dopamine D2 receptors (D2R) in the dorsal striatum (DS) and the nucleus accumbens (Acb) jointly ...
Nutrient Selection in the Absence of Taste Receptor Signaling
(SOC NEUROSCIENCE, 2010)
When allowed to choose between different macronutrients, most animals display a strong attraction toward carbohydrates compared with proteins. It remains uncertain, however, whether this food selection pattern depends ...
Organization of ventral tegmental area projections to the ventral tegmental area-nigral complex in the rat
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
The ventral tegmental area (VTA) is a nodal link in reward circuitry. Based on its striatal output, it has been subdivided in a caudomedial part which targets the ventromedial striatum, and a lateral part which targets the ...
Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors
(Wiley Blackwell Publishing, Inc, 2019-01)
The process of locomotion is controlled by fine-tuned dopaminergic neurons in the Substantia Nigra pars-compacta (SNpc) that projects their axons to the dorsal striatum regulating cortical innervations of medium spiny ...
Increase in locomotor activity after acute administration of the nicotinic receptor agonist 3-bromocytisine in rats
(Elsevier B.V., 2010-02-23)
Nicotinic acetylcholine receptors influence striatal dopaminergic activity and its outcome on motor behavior.
For these reasons, nicotinic receptors have been considered as therapeutically relevant targets for
Parkinson's ...
Increase in locomotor activity after acute administration of the nicotinic receptor agonist 3-bromocytisine in rats
(ELSEVIER, 2010)
Nicotinic acetylcholine receptors influence striatal dopaminergic activity and its outcome on motor behavior.
For these reasons, nicotinic receptors have been considered as therapeutically relevant targets for
Parkinson's ...