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Unravelling the interplay between extracellular acidosis and immune cells
(Hindawi Publishing Corporation, 2018-12)
The development of an acidic tissue environment is a hallmark of a variety of inflammatory processes and solid tumors. However, little attention has been paid so far to analyze the influence exerted by extracellular pH on ...
Cathepsin L3 from fasciola hepatica induces NLRP3 inflammasome alternative activation in murine dendritic cells
(Frontiers Media S.A., 2019-03)
The production of IL-1-family cytokines such as IL-1β and IL-18 is finely regulated by inflammasome activation after the recognition of pathogens associated molecular pattern (PAMPs) and danger associated molecular patterns ...
Proposed model: Mechanisms of immunomodulation induced by probiotic bacteria
(American Society for Microbiology, 2007-05-12)
The mammalian microbiota comprises several hundred different bacterial species, many of which have a beneficial effect on the host. For example, they are involved in preventing colonization of the gut by pathogens and ...
Role Of Innate Immunity-triggered Pathways In The Pathogenesis Of Sickle Cell Disease: A Meta-analysis Of Gene Expression Studies
(NATURE PUBLISHING GROUPLONDON, 2015)
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24
(2022)
Proteasome dysfunction can lead to autoinflammatory disease associated with elevated type I interferon (IFN-αβ) and NF-κB signaling; however, the innate immune pathway driving this is currently unknown. Here, we identified ...
Vías transduccionales asociadas al receptor tipo Toll-4 (TLR4) en la expresión de las proteínas de adhesión VCAM-1 e ICAM-1 en fibroblastos cardiacos
(Universidad de Chile, 2015)
Una consecuencia común de las enfermedades cardiovasculares es la remodelación cardíaca, que se caracteriza por cambios en el tamaño, forma y función del corazón. El infarto agudo al miocardio es la causa más común que ...
The TP53 16-bp duplication polymorphism is enriched in endometriosis patients
(2012)
The main focus of this article is to present the practical aspect of the code rules of variation and the search for a second set of genomic rules, including comparison of sequences to understand how to preserve compatible ...