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Damage index assessment and quality of life in systemic lupus erythematosus patients (with long-term disease) in Northeastern Brazil
(Springer, 2007-03-01)
Systemic lupus erythematosus (SLE) is an autoimmune disease that affects mainly young women. During the disease course, many organs and systems can suffer non-reversible damage that decreases both the patient's life span ...
PIMREG expression level predicts glioblastoma patient survival and affects temozolomide resistance and DNA damage response
(2022-06-01)
PIMREG expression strongly correlates with cellular proliferation in both malignant and normal cells. Throughout embryo development, PIMREG expression is prominent in the central nervous system. Recent studies have described ...
Association of Systemic Lupus International Collaborating Clinics Frailty Index With Damage in Systemic Lupus Erythematosus Patients: Results From a Multiethnic, Multicenter US Cohort of Patients With Lupus
(Wiley, 2022)
Objective. To evaluate the association between the Systemic Lupus International Collaborating Clinics frailty index (SLICC-FI) and damage accrual in systemic lupus erythematosus (SLE) patients.Methods. Patients from the ...
DNA damage and repair in leukocytes of melanoma patients exposed in vitro to cisplatin
(LIPPINCOTT WILLIAMS & WILKINS, 2011)
Resistance to chemotherapeutic drugs can be an obstacle to a successful treatment of cancer patients in part associated with individual response and differences in the DNA repair system. The Comet assay is an informative ...
DNA damage and related modifier genes in Italian Cystic fibrosis patients
(Sociedad de Biología de Chile, 2009)
DNA damage in cytologically normal urothelial cells of patients with a history of urothelial cell carcinoma
(Wiley-Blackwell, 2002-01-01)
In order to determine if patients with a history of previous urothelial cell carcinoma (UCC) but with current normal urinary cytology have DNA damage in urothelial cells, the single-cell gel electrophoresis (comet) assay ...
DNA damage in cytologically normal urothelial cells of patients with a history of urothelial cell carcinoma
(Wiley-Blackwell, 2002-01-01)
In order to determine if patients with a history of previous urothelial cell carcinoma (UCC) but with current normal urinary cytology have DNA damage in urothelial cells, the single-cell gel electrophoresis (comet) assay ...
Metabolic syndrome predicts new damage in systemic lupus erythematosus patients: Data from the Almenara Lupus Cohort
(SAGE Publications, 2022)
Objectives: This study aims to determine whether the MetS predicts damage accrual in SLE patients. Methods: This longitudinal study was conducted in a cohort of consecutive SLE patients seen since 2012 at one single Peruvian ...