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The lipid-mediated hypothesis of fumonisin B1 toxicodynamics tested in model membranes
(Elsevier Science, 2008-06-15)
The disruption of lipidic metabolism was considered a good candidate to explain FB1 toxicity mechanism. In the present work we investigated molecular organizational changes induced by FB1-biomembrane interaction possibly ...
Lipossomas de diferentes composições para entrega intracelular de Quantum Dots
(UNIVERSIDADE FEDERAL DE PERNAMBUCOUFPEBrasilPrograma de Pos Graduacao em Ciencias Biologicas, 2016)
Desenvolvimento e caracterização de sistemas de delivery tópicos para ácido ascórbico: estudos comparativos
(Universidade Federal de São Paulo, 2020-01-30)
O ácido ascórbico ou Vitamina C (Vit C) é um antioxidante potente, capaz de atuar de forma relevante tanto na prevenção quanto no tratamento do processo de envelhecimento cutâneo. No entanto, para apresentar eficácia ...
Intratracheal instillation of lipopolymeric vectors and the effect on mice lung physiology
(Karger, 2012-03)
Background/Aims: The current study compared the effects of intratracheal administration of different lipopolymeric vectors on lung function and histology in normal mice. Methods: Forty-eight BALB/c mice were randomly divided ...
Desenvolvimento de nanosistemas farmacêuticos para terapia gênica
(Universidade Federal do Rio Grande do NorteBRUFRNPrograma de Pós-Graduação em BiotecnologiaBiotecnologia Industrial; Biotecnologia em Agropecuária; Biotecnologia em Recursos Naturais; Biotecn, 2011-03-14)
Gene therapy is one of the major challenges of the post-genomic research and it is based on the transfer of genetic material into a cell, tissue or organ in order to cure or improve the patient s clinical status. In general, ...
Desenvolvimento de sistemas farmacêuticos emulsionados para veiculação gênica
(Universidade Federal do Rio Grande do NorteBRUFRNPrograma de Pós-Graduação em Genética e Biologia MolecularGenética e Biologia Molecular, 2007-02-26)
Broadly speaking, the concept of gene therapy involves the transfer of a genetic material into a cell, tissue, or organ in order to cure a disease or at least improve the clinical status of a patient. Making it simple, ...
Desenvolvimento de nanopartículas de quitossomas como carreadores gênicos
(Universidade Federal de São Paulo (UNIFESP), 2019-07-25)
Chitososomes are nanoparticles formed by interaction between liposomes and chitosan and have of particular interest for biotech applications due to their properties such as ease of production, low cost, storage stability, ...
Correlation of the Physicochemical and Structural Properties of pDNA/Cationic Liposome Complexes with Their in Vitro Transfection
(AMER CHEMICAL SOCWASHINGTON, 2012)
In this study, we characterized the conventional physicochemical properties of the complexes formed by plasmid DNA (pDNA) and cationic liposomes (CL) composed of egg phosphatidylcholine (EPC), 1,2-dioleoyl-sn-glycero-3-p ...
Structural effect of cationic amphiphiles in diacetylenic photopolymerizable membranes
(ELSEVIER IRELAND LTDCLARE, 2012)
Liposomes have been an excellent option as drug delivery systems, since they are able of incorporating lipophobic and/or lipophilic drugs, reduce drug side effects, increase drug targeting, and control delivery. Also, in ...
Relación entre la tutoría y la formación universitaria de los estudiantes de la Facultad de Educación de la Universidad Nacional Federico Villarreal
(Universidad Nacional Federico VillarrealPE, 2022)
El propósito de la investigación es determinar la relación existente entre la Tutoría Universitaria y la Formación Universitaria de los Estudiantes de la Facultad. Durante el desarrollo han existidos limitaciones como la ...