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Genome-wide Transcriptional Analysis of Tetrahymena thermophila Response to Exogenous Cholesterol
(Wiley Blackwell Publishing, Inc, 2020-03)
The ciliate Tetrahymena thermophila does not require sterols for growth and synthesizes pentacyclic triterpenoid alcohols, mainly tetrahymanol, as sterol surrogates. However, when sterols are present in the environment, ...
Phylogenomic analysis of integral diiron membrane histidine motif-containing enzymes in ciliates provides insights into their function and evolutionary relationships
(Academic Press Inc Elsevier Science, 2017-09)
The Integral Membrane Histidine Motif-containing Enzymes (IMHME) are a class of binuclear non-heme iron proteins widely distributed among prokaryotes and eukaryotes. They are characterized by a conserved tripartite motif ...
Hydroxytyrosol prevents reduction in liver activity of Delta - 5 and Delta - 6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high fat diet fed mice
(Biomed Central Ltd., 2017)
Background: Eicosapentaenoic acid (EPA, C20:5n-3), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (AA, C20:4n-6) are long-chain polyunsaturated fatty acids (LCPUFAs) with relevant roles in the organism. EPA and ...
Gene identification and functional characterization of a Δ12 fatty acid desaturase in Tetrahymena thermophila and its influence in homeoviscous adaptation to low temperature
(Elsevier Science, 2019-08)
Homeoviscous adaptation in poikilotherms is based in the regulation of the level of desaturation of fatty acids, variation in phospholipids head groups and sterol content in the membrane lipids, in order to maintain the ...
Fatty acid desaturation in red blood cell membranes of patients with type 2 diabetes is improved by zinc supplementation
(Elsevier, 2020)
Background/Objective: Membrane flexibility can be a determining factor in pathophysiological mechanisms of type 2 diabetes (T2D). As a cofactor of delta-5 desaturase (D5D) and delta-6 desaturase (D6D), and gene expression ...
Effects of dietary sunflower oil on growth parameters, fatty acid profiles and expression of genes regulating growth and metabolism in the pejerrey (Odontesthes bonariensis) fry
(Wiley Blackwell Publishing, Inc, 2018-04)
Aquaculture fish diets usually contain an addition of fish oil to improve their nutritional value. The effect of the replacement of dietary fish oil (FO) by sunflower oil (SfO) on growth, fatty acid composition and expression ...
Effects of dietary polyunsaturated fatty acid sources on expression of lipid‑related genes in bovine milk somatic cells
(Nature, 2020)
The objective of this study was to compare the effect of contrasting sources of dietary n-6 and n-3 PUFA on expression of genes related to lipid metabolism in dairy cows. During 63 days, fifteen lactating cows were assigned ...
Influence of water salinity on genes implicated in somatic growth, lipid metabolism and food intake in Pejerrey (Odontesthes bonariensis)
(Elsevier Science Inc, 2017-08)
Pejerrey, Odontesthes bonariensis, is an euryhaline fish of commercial importance in Argentina. This work aimed to determine if water salinity affects the expression of genes involved in somatic growth (gh; ghr-I; ghr-II; ...
Regulation of growth, fatty acid composition and delta 6 desaturase expression by dietary lipids in gilthead seabream larvae (Sparus aurata)
(2008)
The Δ6 and Δ5 desaturases and elongases show only very limited activity in marine fish, and little is known of the possibility of enhancing Δ6 desaturase gene expression in these fish. The use of plant oils in marine fish ...
Regulation of growth, fatty acid composition and delta 6 desaturase expression by dietary lipids in gilthead seabream larvae (Sparus aurata)
(2008)
The ?6 and ?5 desaturases and elongases show only very limited activity in marine fish, and little is known of the possibility of enhancing ?6 desaturase gene expression in these fish. The use of plant oils in marine fish ...