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Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A systemic review and meta-analysis
Objectives: Coronavirus Disease 2019 (COVID-19) is a new respiratory and systemic disease which needs
quick identification of potential critical patients. This meta-analysis aimed to explore the relationship
between ...
Storm of soluble immune checkpoints associated with disease severity of COVID-19
As the outbreak of coronavirus disease 2019 (COVID-19) turns
into a pandemic, it has literally caused a worldwide public health
crisis. Progressive lymphopenia, especially in T cells, was a
prominent clinical feature ...
Methylprednisolone pulse therapy: An alternative management of severe COVID-19
(Elsevier, 2020)
We present two cases of severe COVID-19 that were rejected by medical institutions. The management of the disease was done at home with methylprednisolone (MP) pulse therapy for three days. This resulted in a favorable ...
Clinical characteristics and diagnostic challenges of pediatric COVID-19: A systematic review and meta-analysis
Background/Purpose: Current studies on pediatric coronavirus disease 2019 (COVID-19) are
rare. The clinical characteristics and spectrum are still unknown. Facing this unknown and
emerging pathogen, we aimed to collect ...
Neuromuscular complications of severe COVID-19 in paediatric patients: Medium-term follow-up
(2022)
Neuromuscular complications in paediatric patients with severe coronavirus disease 2019 (COVID-19) are poorly characterised. However, adult patients with severe COVID-19 reportedly present with frequent neuromuscular ...
A importância da pesquisa clínica na pandemia de covid-19
(Universidade Federal de São Paulo, 2023-06-23)
INTRODUÇÃO: A Pesquisa Clínica é dividida em 4 fases, e é definida como qualquer investigação em seres humanos destinada a descobrir ou verificar os efeitos clínicos (eficácia e segurança) no corpo humano, de um produto ...
Biomarcadores de gravidade da COVID-19
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Biotecnologia - PPGBiotecCâmpus São Carlos, 2022-04-28)
Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, reached pandemic status in 2020, becoming a major global health problem. COVID-19 has a wide spectrum of manifestations, ranging from asymptomatic forms ...
Does poor glucose control increase the severity and mortality in patients with diabetes and COVID-19?
Background and aim: Diabetes in often associated with an increased severity and mortality in patients
with COVID-19. We aimed to find out whether the severity and mortality in patients with diabetes with
COVID-19 has any ...
Working in the dark: Interaction with a sub clinical COVID-19 subject and lessons learned
Subclinical COVID-19 subjects pose a significant challenge. We present a very
close clinical interaction with a subclinical COVID-19 subject that met the “standard screening
criteria” and is unique in several ways. ...
Recovery of severely ill COVID-19 patients by intravenous immunoglobulin (IVIG) treatment: A case series
Introduction: During the recent months, COVID-19 has turned to a global crisis claiming high mortality and
morbidity among populations. Despite the high prevalence of the disease, it has currently no definitive treatment. ...