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Ultrasound-Assisted Syntheses of Chalcones: Experimental Design and Optimization
(Multidisciplinary Digital Publishing Institute, 2019-11)
Chalcones are a group of compounds that belong to the flavonoid family and have a wide variety of uses, including a high therapeutic potential for multiple diseases, such as, anticancer, antifungal or antibacterial agents. ...
Anti-Trichomonas vaginalis activity of chalcone and amino-analogues
(2019-02-14)
Trichomoniasis is the most common non-viral sexually transmitted disease worldwide and can lead to serious consequences in reproductive health, cancer, and HIV acquisition. The current approved treatment present adverse ...
Atividade antimicrobiana de aminochalconas contra células planctônicas e biofilmes
(Universidade Estadual Paulista (Unesp), 2021-11-24)
As infecções nosocomiais são uma das principais causas de mortalidade em todo mundo. O surgimento de agentes antimicrobianos inovadores vem se tornando uma necessidade, uma vez que as altas taxas de infecções são devidas ...
Síntese e atividade anti-HCV, anti-candida e antibacteriana de nitrochalconas
(Universidade Estadual Paulista (Unesp), 2016-03-11)
Chalconas são flavonoides de cadeia aberta com uma cetona α,β-insaturada, a qual separa duas subunidades fenílicas (anéis A e B). Estas substâncias podem ser sintetizadas pela condensação de Claisen-Schmidt e apresentam ...
Síntese e atividade anti-HCV, anti-candida e antibacteriana de nitrochalconas
(Universidade Estadual Paulista (UNESP), 2016)
Síntese de chalconas substituídas e seus híbridos na busca de novos herbicidas
(Universidade Federal de Mato GrossoBrasilInstituto de Ciências Exatas e da Terra (ICET)UFMT CUC - CuiabáPrograma de Pós-Graduação em Química, 2020-03-31)
For several years, the commonly marketed synthetic herbicides have been the
main method of weed management. However, the emergence of herbicide resistance
and its negative effects on both health and the environment ...
Synthesis and DFT calculations of novel vanillin-chalcones and their 3-Aryl-5-(4-(2-(dimethylamino)- ethoxy)-3-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbaldehyde derivatives as antifungal agents
(Molecular Diversity Preservation International, 2017-09)
Novel (E)-1-(aryl)-3-(4-(2-(dimethylamino)ethoxy)-3-methoxyphenyl) prop-2-en-1-ones 4 were synthesized by a Claisen-Schmidt reaction of 4-(2-(dimethylamino)ethoxy)-3-methoxy-benzaldehyde (2) with several acetophenone ...
Síntese e avaliação biológica de fenilidrazonas derivadas de chalconas
(Universidade Federal de Juiz de ForaBrasilICE – Instituto de Ciências ExatasPrograma de Pós-graduação em QuímicaUFJF, 2016)