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Discovery two potent and new inhibitors of 15- lipoxygenase: (E)-3- ((3,4-dihydroxybenzylidene) amino)- 7 - hydroxy-2H-chromen-2-one and (E)- O -(4-(((7-hydroxy-2-oxo-2H-chromen-3-yl) imino) methine) phenyl) dimethylcarbamothioate
(Springer, 2017)
The mechanisms of action and structural determinants
of lipoxygenases inhibitors have been explored on
several occasions, but many questions remain unanswered,
especially about the differences of the inhibition ...
Discovery two potent and new inhibitors of 15-lipoxygenase: (E)-3-((3,4-dihydroxybenzylidene) amino)-7-hydroxy-2H-chromen-2-one and (E)-O-(4-(((7-hydroxy-2-oxo-2H-chromen-3-yl) imino)methine)phenyl)dimethylcarbamothioate
(Birkhauser Boston, 2017)
The mechanisms of action and structural determinants of lipoxygenases inhibitors have been explored on several occasions, but many questions remain unanswered, especially about the differences of the inhibition mechanisms ...
Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae)
(Elsevier B.V., 2007-08-01)
The biosynthesis of (2S)-2-methyl-2-(4'-methyl-3-pentenyl)-8-(3-methyl-2-butenyl)-2H-1-benzopyran-6-carboxylic acid (gaudichaudianic acid), the major metabolite in leaves and roots of Piper gaudichaudianum Kunth (Piperaceae), ...
Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae)
(Elsevier B.V., 2007-08-01)
The biosynthesis of (2S)-2-methyl-2-(4'-methyl-3-pentenyl)-8-(3-methyl-2-butenyl)-2H-1-benzopyran-6-carboxylic acid (gaudichaudianic acid), the major metabolite in leaves and roots of Piper gaudichaudianum Kunth (Piperaceae), ...
Absolute configuration of sargaol acetate using DFT calculations and vibrational circular dichroism
(2010)
The absolute configuration (AC) of sargaol acetate (2), isolated from the brown alga Stypopodium flabelliforme, was determined using vibrational circular dichroism (VCD) measurements and density functional theory (DFT) ...
Chromenopyridines: Promising scaffolds for medicinal and biological chemistry
(2011)
Chromenopyridines constitute a structurally diverse class of compounds with a wide range of bioactivities and increasing presence in drugs. Here we analyze the scope of the synthetic methodology to access this nucleus with ...
Long-range correlations (nj C,H n > 3) in the HMBC spectra of 3-(4-oxo-4H-chromen-3-YL)-acrylic acid ethyl esters
(Sociedade Brasileira de Quimica, 2005)
A systematic study about the long-range correlations observed in the HMBC spectra of a series of cis and trans 3-(4-oxo-4H-chromen-3-yl)-acrylic acid ethyl esters, and 5-hydroxy derivatives, was carried out. The results ...
Plastoquinones and a chromene isolated from the antarctic brown alga Desmarestia menziesii
(1996)
(2'E, 6'E, 10'E, 14'E)-2-(8',9'-dione-3', 7', 11', 15'-tetramethylhexadeca-2', 6', 10', 14'-tetraenyl)-6-Methyl-1,4-benzoquinone, (2'E, 6'E, 10'E, 14'E)-2-(8'-one, 15'-formyl-3', 7', 11', trimethylhexadeca-2', 6', 10', ...
Síntese de 1-(selenobutil)-2-fenil-4h-selenofeno[2,3-c]cromenos via reação de ciclização cascata mediada por FeCl3
(Universidade Federal de Santa MariaBrasilQuímicaUFSMPrograma de Pós-Graduação em QuímicaCentro de Ciências Naturais e Exatas, 2020-02-21)
The synthesis of heterocyclic compounds is of great importance within the
chemistry of materials and the biological area, targeting both the chemical industry and
the pharmaceutical industry. Among the different heteroatoms ...