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Central chemoreceptors and neural mechanisms of cardiorespiratory control
(Associação Brasileira de Divulgação Científica, 2011)
The arterial partial pressure (P CO2) of carbon dioxide is virtually constant because of the close match between the metabolic production of this gas and its excretion via breathing. Blood gas homeostasis does not rely ...
ATP in the lateral hypothalamus/perifornical area enhances the CO2 chemoreflex control of breathing
(2018-12-01)
New Findings: What is the central question of this study? ATP is known to modulate the chemosensitivity of some brain areas. However, whether the ATP contributes specifically to the mechanism of chemoreception in the lateral ...
Contribution of peripheral and central chemoreceptors to sympatho-excitation in heart failure
(2017)
Chronic heart failure (CHF) is a major public health problem. Tonic hyper-activation of sympathetic neural outflow is commonly observed in patients with CHF. Importantly, sympatho-excitation in CHF exacerbates its progression ...
Revisiting the physiological effects of exercise training on autonomic regulation and chemoreflex control in heart failure: Does ejection fraction matter?
(American Physiological Society, 2018)
Differential effects of ventilatory stimulation by sex hormones and almitrine on hypoxic erythrocytosis
(Pflugers Arch-Eur J Physiol, 1997)
Abstract In the absence of pulmonary disease, hypoventilation is considered to be the primary cause of
Chronic Mountain Sickness, and there is some reason to
believe that chronic administration of respiratory analeptics ...
Rostral ventrolateral medullary catecholaminergic neurones mediate irregular breathing pattern in volume overload heart failure rats
(WILEY, 2019)
Key points A strong association between disordered breathing patterns, elevated sympathetic activity, and enhanced central chemoreflex drive has been shown in experimental and human heart failure (HF). The aim of this study ...
Neurochemical and electrical modulation of the locus coeruleus: contribution to CO2drive to breathe
(2014)
The locus coeruleus (LC) is a dorsal pontine region, situated bilaterally on the floor of the fourth ventricle. It is considered to be the major source of noradrenergic innervation in the brain. These neurons are highly ...
Ventilatory and Autonomic Regulation in Sleep Apnea Syndrome: A Potential Protective Role for Erythropoietin?
(FRONTIERS MEDIA SA, 2018)
Obstructive sleep apnea (OSA) is the most common form of sleep disordered breathing and is associated with wide array of cardiovascular morbidities. It has been proposed that during OSA, the respiratory control center (RCC) ...