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Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.
(2013)
The canonical Sonic Hedgehog (Shh)/Gli pathway plays multiples roles during central nervous system (CNS) development. To elucidate the molecular repertoire of Shh mediators, we have recently described novel transcriptional ...
Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.
(2013)
The canonical Sonic Hedgehog (Shh)/Gli pathway plays multiples roles during central nervous system (CNS) development. To elucidate the molecular repertoire of Shh mediators, we have recently described novel transcriptional ...
The low molecular weight S-nitrosothiol, S-nitroso-N-acetylpenicillamine, promotes cell cycle progression in rabbit aortic endothelial cells
(Elsevier B.V., 2008-06-01)
S-Nitrosylation reactions are considered to be a major mechanism by which NO-related bioactivities are regulated in vivo. in the present study, we show the effects of the low molecular weight S-nitrosothiol, S-nitroso-N- ...
Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase
(Nature Publishing Group, 2017-06)
Upon different types of stress, the gene encoding the mitosis-promoting phosphatase Cdc25C is transcriptionally repressed by p53, contributing to p53’s enforcement of a G2 cell cycle arrest. In addition, Cdc25C protein ...
Akt1 intramitochondrial cycling is a crucial step in the redox modulation of cell cycle progression
(Public Library of Science, 2009-10)
Akt is a serine/threonine kinase involved in cell proliferation, apoptosis, and glucose metabolism. Akt is differentially activated by growth factors and oxidative stress by sequential phosphorylation of Ser473 by mTORC2 ...