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The synergy between structural stability and DNA-binding controls the antibody production in EPC/DOTAP/DOPE liposomes and DOTAP/DOPE lipoplexes
(ELSEVIER SCIENCE BV, 2009)
We present a comparative study of the physico-chemical properties, in vitro cytotoxicity and in vivo antibody production of surface-complexed DNA in EPC/DOTAP/DOPE (50/25/25% molar) liposomes and DOTAP/DOPE (50/50% molar) ...
DNA alters the bilayer structure of cationic lipid diC14-amidine: A spin label study
(ELSEVIER SCIENCE BV, 2009)
Cationic lipids-DNA complexes (lipoplexes) have been used for delivery of nucleic acids into cells in vitro and in vivo. Despite the fact that, over the last decade, significant progress in the understanding of the cellular ...
Recombinant Protein-based Nanocarriers And Their Association With Cationic Liposomes: Characterization And In Vitro Evaluation
(Elsevier Science BVAmsterdam, 2017)
Dioctadecyldimethylammonium:Monoolein Nanocarriers for Efficient in Vitro Gene Silencing
(Amer Chemical Soc, 2014-05-14)
This study describes a novel liposomal formulation for siRNA delivery, based on the mixture of the neutral lipid mono olein (MO) and cationic lipids of the dioctadecyldimethylammonium (DODA) family. The cationic lipids ...
Structural effect of cationic amphiphiles in diacetylenic photopolymerizable membranes
(Elsevier Ireland, 2012-12)
Liposomes have been an excellent option as drug delivery systems, since they are able of incorporating lipophobic and/or lipophilic drugs, reduce drug side effects, increase drug targeting, and control delivery. Also, in ...