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The carbonic anhydrase domain of plant mitochondrial complex I
(Wiley Blackwell Publishing, Inc, 2016-07)
The mitochondrial NADH dehydrogenase complex (complex I) consists of several functional domains which independently arose during evolution. In higher plants, it contains an additional domain which includes proteins resembling ...
Functional characterization of mutants affected in the carbonic anhydrase domain of the respiratory complex I in Arabidopsis thaliana
(Wiley, 2015-09)
The NADH–ubiquinone oxidoreductase complex (complex I) (EC 1.6.5.3) is the main entrance site of electrons into the respiratory chain. In a variety of eukaryotic organisms, except animals and fungi (Opisthokonta), it ...
Inhibition of the β-carbonic anhydrases from Mycobacterium tuberculosis with C-cinnamoyl glycosides: Identification of the first inhibitor with anti-mycobacterial activity
(Pergamon-Elsevier Science Ltd., 2013-01)
A small series of C-cinnamoyl glycoside containing the phenol moiety was tested for the inhibition of the three Mycobacterium tuberculosis b-carbonic anhydrases (CAs, EC 4.2.1.1) with activities in the low micromolar range ...
N-β-Glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII
(Pergamon-Elsevier Science Ltd, 2011-08)
The transmembrane isoforms of carbonic anhydrase (CA IX and XII) have been shown to be linked to carcinogenesis and their inhibition to arrest primary tumor and metastases growth. In this Letter, we present a series of ...
Total body zinc depletion and its relationship to the development of hyperprolactinemia in chronic renal insufficiency
(Editrice Kurtis S R LMilanoItália, 1996)
Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence
(Elsevier Science, 2019-09-01)
This paper reports results of a valuable study on investigation of inhibitory effects of the sulfonamide derivative of quercetin (QD) on human carbonic anhydrase II (CA-II) by electrochemical and chemometrical approaches. ...
Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action
(Pergamon-Elsevier Science Ltd., 2016-02-15)
A set of N,N0 -disubstituted sulfamides and sodium cyclamate have been tested for their inhibitory action against six isoforms of carbonic anhydrase (CA, EC 4.2.1.1) found in the brain, that is, CA I, CA II, CA VII, CA IX, ...
Gamma carbonic anhydrases are subunits of the mitochondrial complex I of diatoms
(Wiley Blackwell Publishing, Inc, 2021-02)
Diatoms are unicellular organisms containing red algal-derived plastids that probably originated as result of serial endosymbioses between an ancestral heterotrophic organism and a red alga or cryptophyta algae from which ...
Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties
(Academic Press Inc Elsevier Science, 2018-02)
One of the most successful approaches for designing carbonic anhydrase (CA, EC 4.2.1.1) inhibitors was denominated ‘the sugar approach’. The sugar approach consists in attaching different carbohydrates to CA inhibiting ...