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The role of mitochondria and biotransformation in abamectin-induced cytotoxicity in isolated rat hepatocytes
(2013-03-01)
Abamectin (ABA), which belongs to the family of avermectins, is used as a parasiticide; however, ABA poisoning can impair liver function. In a previous study using isolated rat liver mitochondria, we observed that ABA ...
The role of mitochondria and biotransformation in abamectin-induced cytotoxicity in isolated rat hepatocytes
(2013-03-01)
Abamectin (ABA), which belongs to the family of avermectins, is used as a parasiticide; however, ABA poisoning can impair liver function. In a previous study using isolated rat liver mitochondria, we observed that ABA ...
Accumulation of human pharmaceuticals and biotransformation enzymes in fish from two areas of the lower Rio de la Plata Basin
(Elsevier, 2020-11-15)
The accumulation of four human pharmaceuticals active compounds (HPhAC) in the muscle of four fish species of the Rio de la Plata Basin were assessed regarding the compound logP and pKa, and fish trophic levels. For ...
Modificação de óleos e gorduras por biotransformaçãoModification of oils and fats by biotransformation
(Sociedade Brasileira de Química, 2004)
Improving the chemopreventive potential of orange juice by enzymatic biotransformation
(Elsevier Science BvAmsterdamHolanda, 2013)
Drug Metabolism
(Springer Nature Switzerland AG, 2018)
Through evolution, the body has developed different strategies to dispose metabolic 4waste and protect itself from exposure to potential toxic chemicals. It is useful to differentiate chemical compounds with a well-defined ...
Regio- and enantio selective reduction of methyleneketoesters mediated by Saccharomyces cerevisiae
(Elsevier Science BvAmsterdamHolanda, 2007)
Modulation of Biotransformation Systems and ABC Transporters by Benznidazole in Rats
(American Society for Microbiology, 2013-10)
The effect of antichagasic benznidazole (BZL; 100mg/kg body weight/day, 3 consecutive days, intraperitoneally) on biotransfor-mation systems and ABC transporters was evaluated in rats. Expression of cytochrome P-450 (CYP3A), ...
Biotransformation of dehydro-epi-androsterone by Aspergillus parasiticus: Metabolic evidences of BVMO activity
(Elsevier Science Inc, 2016-05)
The research on the synthesis of steroids and its derivatives is of high interest due to their clinical applications. A particular focus is given to molecules bearing a D-ring lactone like testolactone because of its ...
Biotransformations
(Asiatech Publishers, 2008)