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Transcriptional upregulation of four genes of the lysine biosynthetic pathway by homocitrate accumulation in Penicillium chrysogenum: homocitrate as a sensor of lysine-pathway distress
(Society for General Microbiology, 2009-12)
The lysine biosynthetic pathway has to supply large amounts of α-aminoadipic acid for penicillin biosynthesis in Penicillium chrysogenum. In this study, we have characterized the P. chrysogenum L2 mutant, a lysine auxotroph ...
Isolation and characterization of the gibberellin biosynthetic gene cluster in Sphaceloma manihoticola
(2008)
Gibberellins (GAs) are tetracyclic diterpenoid phytohormones that were first identified as secondary metabolites of the fungus Fusarium fujikuroi (teleomorph, Gibberella fujikuroi). GAs were also found in the cassava ...
Genomics of pyrrolnitrin biosynthetic loci: evidence for conservation and whole-operon mobility within Gram-negative bacteria
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Pyrrolnitrin (PRN) is a tryptophan-derived secondary metabolite produced by a narrow range of Gram-negative bacteria. The PRN biosynthesis by rhizobacteria presumably has a key role in their life strategies and in the ...
Genetic Organization of Anabaenopeptin and Spumigin Biosynthetic Gene Clusters in the Cyanobacterium Sphaerospermopsis torquesreginae ITEP-024
(Amer Chemical Soc, 2017-03-01)
Cyanobacteria produce a broad range of natural products, many of which are potent protease inhibitors. Biosynthetic gene dusters encoding the production of novel protease inhibitors belonging to the spumigin and anabaenopeptin ...
De novo assembly and functional annotation of Myrciaria dubia fruit transcriptome reveals multiple metabolic pathways for L-ascorbic acid biosynthesis
(BioMed Central, 2015)
Background. Myrciaria dubia is an Amazonian fruit shrub that produces numerous bioactive phytochemicals, but is best known by its high L-ascorbic acid (AsA) content in fruits. Pronounced variation in AsA content has been ...
De novo synthesis of benzenoid compounds by the yeast hanseniaspora vineae increases the flavor diversity of wines
(American Chemical Society, 2016-06)
Benzyl alcohol and other benzenoid-derived metabolites of particular importance in plants confer floral and fruity flavors to wines. Among the volatile aroma components in Vitis vinifera grape varieties, benzyl alcohol is ...
Major kinds of drug targets in chagas disease or american trypanosomiasis
(Bentham Science Publishers, 2019-08-21)
American Trypanosomiasis, a parasitic infection commonly named Chagas disease, affects millions of people all over Latin American countries. Presently, the World Health Organization (WHO) predicts that the number of ...