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Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2005-12)
Ischemic injuries are associated with several pathological conditions, including stroke and myocardial infarction. Several studies have indicated extensive apoptotic cell death in the infarcted area as well as in the ...
Histomorfometria, apoptose (Bcl-2 e Bax) e marcador de proliferação celular ki-67 em neoplasias intraepiteliais do colo uterino
(Universidade Federal de Minas GeraisUFMG, 2011-02-24)
Cervical dysplasias are precursor to the squamous cell carcinoma (SCC) of the uterine cervix. Carcinogen induced mutations can be correlated with proliferative alterations. Accumulation of such mutations overlaps the genomic ...
Bcl-X-L inhibits Bax-induced alterations in mitochondrial respiration and calcium release
(Elsevier B.V., 2008-09-12)
Apoptosis is a natural cell elimination process involved in a number of physiological and pathological events. This process can be regulated by members of the Bcl-2 family. Bax, a pro-apoptotic member of this family, ...
Immunohistochemical expression of PCNA, p53, bax and bcl-2 in oral lichen planus and epithelial dysplasia.
(2009-03-01)
The potential for malignant transformation of oral lichen planus is still controversial. The expression of proteins related to cell proliferation and apoptosis in oral lichen planus and epithelial dysplasia was analyzed ...
Immunohistochemical expression of PCNA, p53, bax and bcl-2 in oral lichen planus and epithelial dysplasia.
(2009-03-01)
The potential for malignant transformation of oral lichen planus is still controversial. The expression of proteins related to cell proliferation and apoptosis in oral lichen planus and epithelial dysplasia was analyzed ...
A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX
(Embo Press, 2012-03)
The cellular response to p53 activation varies greatly in a stimulus‐ and cell type‐specific manner. Dissecting the molecular mechanisms defining these cell fate choices will assist the development of effective p53‐based ...
BAX326 (RIXUBIS): a novel recombinant factor IX for the control and prevention of bleeding episodes in adults and children with hemophilia B
(SAGE Publications LtdReino Unido, 2014)
Abstract: Hemophilia B management has improved considerably since the introduction of
high-purity plasma-derived factor IX (pdFIX) products in the early 1990s. Recombinant FIX
(rFIX) was introduced more recently and has ...
Método de integração semântica incremental de dados científicos baseado em ontologias
(Universidade Federal de Minas GeraisBrasilECI - DEPARTAMENTO DE TEORIA E GESTÃO INFORMAÇÃOUFMG, 2019)
Grafos de conhecimento para preparação e reutilização de dados científicos
(Universidade Federal de Minas GeraisBrasilECI - DEPARTAMENTO DE TEORIA E GESTÃO INFORMAÇÃOUFMG, 2019)