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Efeitos do treinamento físico na adiposidade visceral, tecido adiposo marrom e parâmetros metabólicos de ratos Wistar alimentados com dieta hiperlipídica
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2020-07-15)
Obesity is a multifactorial disease that produces various metabolic disorders through the local and systemic inflammatory response occasioned by the pathological remodeling of visceral white adipose tissue (WAT). Furthermore, ...
Spheroids derived from the stromal vascular fraction of adipose tissue self-organize in complex adipose organoids and secrete leptin
(2023)
Abstract
Background
Adipose tissue-derived stromal vascular fraction (SVF) harbors multipotent cells with potential therapeutic relevance. We developed a method to form ...
Nutritional and non-nutritional agents that stimulate white adipose tissue browning
(Springer New York LLC, 2019)
Obesity is a public health problem present in both developed and developing countries. The white adipose tissue (WAT) is the main deposit of lipids when there is an excess of energy. Its pathological growth is directly ...
n-3 polyunsaturated fatty acids in the regulation of adipose tissue browning and thermogenesis in obesity: Potential relationship with gut microbiota
(2021)
Background: Obesity is a worldwide public health problem characterized by fat tissue accumulation, favouring adipose tissue and metabolic alterations. Increasing energy expenditure (EE) through brown adipose tissue activation ...
Brown fat organogenesis and maintenance requires AKT1 and AKT2
(Elsevier Gmbh, 2019-05)
Objective: Understanding the signaling mechanisms that control brown adipose tissue (BAT) development is relevant to understanding energy homeostasis and obesity. The AKT kinases are insulin effectors with critical in vivo ...
Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity
(Elsevier, 2020-10)
Objectives: Typically, obesity results from an inappropriate balance between energy uptake from nutrient consumption and burning of calories, which leads to a pathological increase in fat mass. Obesity is a major cause of ...
Genetics informs precision practice in the diagnosis and management of pheochromocytoma
(BioScientifica Ltd., 2018)
© 2018 Society for Endocrinology Published by Bioscientifica Ltd. Although the authors of the present review have contributed to genetic discoveries in the field of pheochromocytoma research, we can legitimately ask whether ...
Mechanisms involved in the loss of brown adipose tissue in the AGPAT2 deficient mouse
(2019)
1-acylglycerol-3-phosphate O-acyltransferase-2 (AGPAT2) is an enzyme that participates in the synthesis of triacylglycerols and glycerophospholipids. In the differentiation of adipocytes (adipogenesis) the storage of lipids ...