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Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines
(Pergamon-Elsevier Science Ltd, 2010-01)
The synthesis and full 3D structural characterization of nine new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinoline derivatives are reported. These belong to a library whose rationale for the design was the previous ...
Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents
(Elsevier France-editions Scientifiques Medicales Elsevier, 2013-11)
As a part of our project pointed at the search of new safe chemotherapeutic and chemoprophylactic agents against parasitic diseases, several compounds structurally related to 4-phenoxyphenoxyethyl thiocyanate (WC-9), which ...
Antiparasitic effect of vitamin B12 on Trypanosoma cruzi
(American Society for Microbiology, 2012-10)
A nutritional characteristic of trypanosomatid protozoa is that they need a heme compound as a growth factor. Because of the cytotoxic activity of heme and its structural similarity to cobalamins, we have investigated the ...
Activation of Caenorhabditis elegans Levamisole-Sensitive and Mammalian Nicotinic Receptors by the Antiparasitic Bephenium
(American Society for Pharmacology and Experimental Therapeutics, 2018-11)
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels involved in neuromuscular transmission. In nematodes, muscle nAChRs are targets of antiparasitic drugs. Bephenium is an anthelmintic compound whose ...
Desenvolvimento de método para determinação de resíduos de antiparasitários em leite bovino empregando LLE-LTP E LC-MS/MS
(Universidade Federal de Santa MariaBrasilQuímicaUFSMPrograma de Pós-Graduação em QuímicaCentro de Ciências Naturais e Exatas, 2016-08-26)
Milk is one of the most consumed fresh food, considered a nutritionally
complete product. Veterinary drugs are used in order to increase productivity.
However, improper use of these products may result in the presence ...
Antiparasitic bromotyrosine derivatives from the marine sponge Verongula rigida
(MDPIProductos Naturales MarinosPrograma de Estudio y Control de Enfermedades Tropicales (PECET)Suiza, 2020)
Constituents from stem barks of Luehea ochrophylla Mart and evaluation of their antiparasitic, antimicrobial, and antioxidant activities
(Taylor & Francis Health Sciences, 2019)
A search for new antiparasitic agents
(Acta Andina, 1993)
In connection with our previous work in the field of quinone chemistry and the potential pharmaceutical value of these compounds, we have begun a search for antiprotozoal activity of some synthetic substances. In a first ...
A search for new antiparasitic agents
(Acta Andina, 1993)