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Biocompatible microemulsion modifies the pharmacokinetic profile and cardiotoxicity of doxorubicin
(2013-01-01)
Doxorubicin (DOX) is an anthracycline antibiotic with a broad antitumor spectrum. However, the clinical use of DOX is limited because of its cardiotoxicity, a dose-dependent effect. Colloidal drug delivery systems, such ...
Biocompatible microemulsion modifies the pharmacokinetic profile and cardiotoxicity of doxorubicin
(2013-01-01)
Doxorubicin (DOX) is an anthracycline antibiotic with a broad antitumor spectrum. However, the clinical use of DOX is limited because of its cardiotoxicity, a dose-dependent effect. Colloidal drug delivery systems, such ...
Plication of the free wall of the left ventricle in dogs with doxorubicin-induced cardiomyopathy
(2005-02-01)
Objective - To evaluate plication of the free wall of the left ventricle, which reduces the left ventricular area and volume, as a method to improve the left ventricular systolic function without cardiopulmonary bypass. ...
Neurohormonal, hemodynamic, and electrocardiographic evaluations of healthy dogs receiving long-term administration of doxorubicin
(2006-08-01)
Objective - To evaluate diagnostic testing that could be used to establish an early diagnosis of cardiotoxicosis induced by long-term administration of doxorubicin. Animals - 13 adult mixed-breed dogs. Procedures - 7 dogs ...
Ventricular Systolic Reserve in Asymptomatic Children Previously Treated With Low Doses of Anthracyclines
(2007-10-15)
Doppler echocardiography has been used for the diagnosis of anthracycline-induced cardiotoxicity. However, few data are available that include asymptomatic children previously treated with a low cumulative dose of this ...
Ventricular Systolic Reserve in Asymptomatic Children Previously Treated With Low Doses of Anthracyclines
(2007-10-15)
Doppler echocardiography has been used for the diagnosis of anthracycline-induced cardiotoxicity. However, few data are available that include asymptomatic children previously treated with a low cumulative dose of this ...
Neurohormonal, hemodynamic, and electrocardiographic evaluations of healthy dogs receiving long-term administration of doxorubicin
(2006-08-01)
Objective - To evaluate diagnostic testing that could be used to establish an early diagnosis of cardiotoxicosis induced by long-term administration of doxorubicin. Animals - 13 adult mixed-breed dogs. Procedures - 7 dogs ...