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Angiotensin II type 1 receptor blockade partially attenuates hypoxia-induced pulmonary hypertension in newborn piglets: relationship with the nitrergic system
(ASSOC BRAS DIVULG CIENTIFICASAO PAULO, 2012)
The objective of this study was to observe possible interactions between the renin-angiotensin and nitrergic systems in chronic hypoxia-induced pulmonary hypertension in newborn piglets. Thirteen chronically instrumented ...
The role of the angiotensin II type I receptor blocker telmisartan in the treatment of non-alcoholic fatty liver disease: a brief review
(Universidade Federal de Minas GeraisBrasilICA - INSTITUTO DE CIÊNCIAS AGRÁRIASUFMG, 2018-04-10)
Blockage of Angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation
(DR DIETRICH STEINKOPFF VERLAG, 2010)
Although most of effects of Angiotensin II (Ang II) related to cardiac remodelling can be attributed to type 1 Ang II receptor (AT(1)R), the type 2 receptor (AT(2)R) has been shown to be involved in the development of some ...
Thyroid Hormone Increases TGF-beta 1 in Cardiomyocytes Cultures Independently of Angiotensin II Type 1 and Type 2 Receptors
(HINDAWI PUBLISHING CORPORATION, 2010)
TH-induced cardiac hypertrophy in vivo is accompanied by increased cardiac Transforming Growth Factor-beta 1 (TGF-beta 1) levels, which is mediated by Angiotensin II type 1 receptors (AT1R) and type 2 receptors (AT2R). ...
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system
(PORTLAND PRESS LTD, 2014)
Chronic RAS (renin-angiotensin system) activation by both AngII (angiotensin II) and aldosterone leads to hypertension and perpetuates a cascade of pro-hypertrophic, pro-inflammatory, pro-thrombotic and atherogenic effects ...
Angiotensin II type 2 receptor (AT2R) is associated with increased tolerance of the hyperthyroid heart to ischemia-reperfusion
(Martinus Nijhoff PubNorwel, 2013-10)
Background Thyroid hormone induces cardiac hypertrophy and preconditions the myocardium against Ischemia/Reperfusion (I/R) injury. Type 2 Angiotensin II receptors (AT2R) are shown to be upregulated in cardiac hypertrophy ...
Renin-angiotensin-aldosterone system and COVID-19 infection
With the multiplication of COVID-19 severe acute respiratory syndrome cases due to SARS-COV2, some
concerns about angiotensin-converting enzyme 1 (ACE1) inhibitors (ACEi) and angiotensin II type 1
receptor blockers (ARB) ...
Avaliação do perfil das angiotensinas em pacientes cardiopatas submetidos a angioplastia percutânea
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2020-07-08)
Introduction: According to the Brazilian Society of Cardiology, in Brazil there is 1 death from cardiovascular causes every 90 seconds and cardiovascular disease causes twice as many deaths as those due to all types of ...
Reduction of Inducible Nitric Oxide Synthase via Angiotensin Receptor Blocker Prevents the Oxidative Retinal Damage in Diabetic Hypertensive Rats
(Taylor & Francis IncPhiladelphiaEUA, 2010)