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Amerindian ancestry and extended longevity in Nicoya, Costa Rica
(2018-01)
Objectives: The aim of this study was to address the hypothesis that Amerindian
ancestry is associated with extended longevity in the admixed population of Nicoya,
Costa Rica. The Nicoya Peninsula of Costa Rica has been ...
Amerindian ancestry and extended longevity in Nicoya, Costa Rica
(2018-01)
Objectives: The aim of this study was to address the hypothesis that Amerindian
ancestry is associated with extended longevity in the admixed population of Nicoya,
Costa Rica. The Nicoya Peninsula of Costa Rica has been ...
European Ancestry Predominates in Neuromyelitis Optica and Multiple Sclerosis Patients from Brazil
(2013-03-20)
Background: Neuromyelitis optica (NMO) is considered relatively more common in non-Whites, whereas multiple sclerosis (MS) presents a high prevalence rate, particularly in Whites from Western countries populations. However, ...
European Ancestry Predominates in Neuromyelitis Optica and Multiple Sclerosis Patients from Brazil
(2013-03-20)
Background: Neuromyelitis optica (NMO) is considered relatively more common in non-Whites, whereas multiple sclerosis (MS) presents a high prevalence rate, particularly in Whites from Western countries populations. However, ...
Extended HLA-G genetic diversity and ancestry composition in a Brazilian admixed population sample: Implications for HLA-G transcriptional control and for case-control association studies
(2018-11-01)
Human leukocyte antigen-G (HLA-G) is a nonclassical Major Histocompatibility Complex (MHC) molecule with immunomodulatory function and restricted tissue expression. The genetic diversity of HLA-G has been extensively studied ...
Distribution of ABCB1 polymorphisms among Brazilians: impact of population admixture
(FUTURE MEDICINE LTD, 2008)
Introduction: Interethnic admixture is a source of cryptic population structure that may lead to spurious genotype-phenotype associations in pharmacogenomic studies. We studied the impact of population stratification on ...
Humoral immune responses against the malaria vaccine candidate antigen Plasmodium vivax AMA-1 and IL-4 gene polymorphisms in individuals living in an endemic area of the Brazilian Amazon
(Elsevier B.V., 2015-08-01)
Background: Several studies have recently demonstrated that the immune responses against malaria is governed by different factors, including the genetic components of the host. The IL-4 gene appears to be a strong candidate ...
Ancestry Informative Markers Clarify the Regional Admixture Variation in the Costa Rican Population
(Human Biology Open Access Pre-Prints. Paper 34., 2013-10-09)
Study for the first time a random sample from all regions of the country with AIMS (Ancestry Informative Markers) to address the individual and regional admixture proportions. A sample of 160 male individuals was screened ...
Ancestry Informative Markers Clarify the Regional Admixture Variation in the Costa Rican Population
(Human Biology Open Access Pre-Prints. Paper 34., 2013-10-09)
Study for the first time a random sample from all regions of the country with AIMS (Ancestry Informative Markers) to address the individual and regional admixture proportions. A sample of 160 male individuals was screened ...