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Effects of combined nicotine and fluoxetine treatment on adult hippocampal neurogenesis and conditioned place preference
(Elsevier, 2015-08)
Adult neurogenesis occurs in mammals within the dentate gyrus, a hippocampal subarea. It is known to be induced by antidepressant treatment and reduced in response to nicotine administration. We checked here whether the ...
Frizzled-1 receptor regulates adult hippocampal neurogenesis
(BioMed Central Ltd., 2016)
© 2016 Mardones et al. Background: In the adult hippocampus new neurons are continuously generated from neural stem cells (NSCs) present at the subgranular zone of the dentate gyrus. This process is controlled by Wnt ...
Spinal Cord Injury Leads to Hippocampal Glial Alterations and Neural Stem Cell Inactivation
(Springer/Plenum Publishers, 2020-06)
The hippocampus encodes spatial and contextual information involved in memory and learning. The incorporation of new neurons into hippocampal networks increases neuroplasticity and enhances hippocampal-dependent learning ...
Similar GABAergic inputs in dentate granule cells born during embryonic and adult neurogenesis
(Wiley Blackwell Publishing, Inc, 2007-05)
Neurogenesis in the dentate gyrus of the hippocampus follows a unique temporal pattern that begins during embryonic development, peaks during the early postnatal stages and persists through adult life. We have recently ...
A Price to Pay for Adult Neurogenesis
(American Association For The Advancement Of Science, 2014-05)
We tend to believe that plasticity is what makes brain circuits adaptable to continuous changes in environmental demands and that greater brain plasticity should result in a better ability to cope with the surrounding ...
Local Klotho Enhances Neuronal Progenitor Proliferation in the Adult Hippocampus
(2019)
Klotho is an aging-related protein associated with hippocampal cognitive performance in mammals. Klotho regulates progenitor cell proliferation in non-neuronal tissues, but its role in adult hippocampal neurogenesis (AHN) ...
Local Klotho Enhances Neuronal Progenitor Proliferation in the Adult Hippocampus
(2019)
Klotho is an aging-related protein associated with hippocampal cognitive performance in mammals. Klotho regulates progenitor cell proliferation in non-neuronal tissues, but its role in adult hippocampal neurogenesis (AHN) ...
Requirement of Adult-Born Neurons for Hippocampus-Dependent Learning
(Elsevier Science, 2012-02)
A fundamental question in the field of adult neurogenesis relies in addressing whether neurons generated in the adult dentate gyrus are needed for hippocampal function. Increasing evidence is accumulating in support of the ...