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An open randomized study comparing immunosuppression therapy initiated before or after kidney transplantation in haploidentical living recipients
(Blackwell Munksgaard, 2004-08-01)
Background: Acute rejection is the most important risk factor for graft survival. Although many centers start immunosuppressive therapy days before the surgery in living donors, there is no systematic study concerning the ...
Detection of the Tim-3 ligand, galectin-9, inside the allograft during a rejection episode
(ELSEVIER SCIENCE BV, 2009)
Introduction: Tim-3 is a Th1 lymphocytes membrane protein with inhibitory function. Its ligand, galectin-9, was recently identified and it is expressed in some lymphocyte subpopulation. In addition, endothelial cells and ...
In situ expression of mononuclear cell markers and interleukin-2 receptor in renal allograft biopsies of acute rejection and borderline cases
(2007-01-01)
The correct diagnosis of renal allograft rejection may be difficult using only clinical and/or histopathological criteria. Immunological assays should be considered in order to evaluate the phenotype of inflammatory ...
In situ expression of mononuclear cell markers and interleukin-2 receptor in renal allograft biopsies of acute rejection and borderline cases
(2007-01-01)
The correct diagnosis of renal allograft rejection may be difficult using only clinical and/or histopathological criteria. Immunological assays should be considered in order to evaluate the phenotype of inflammatory ...
High expression of TIM-3 mRNA in urinary cells from kidney transplant recipients with acute rejection
(Blackwell Publishing, 2007-06-01)
TIM-3 is a recently described molecule specifically expressed on Th1 differentiated T cells. We explored the usefulness of urinary mRNA profiles in the diagnosis of renal acute rejection (AR). Sixty urinary samples from ...
Plasma proteomics for the assessment of acute renal transplant rejection
(Pergamon-Elsevier Science Ltd, 2016)
Renal transplant is the best treatment for patients with chronical kidney disease however acute graft rejection is the major impediment to success in renal transplantation leading to loss of the organ the first year after ...
Human leukocyte antigen-G expression after kidney transplantation is associated with a reduced incidence of rejection
(ELSEVIER SCIENCE BV, 2008)
HLA-G is a non-classic Human Leukocyte Antigen (HLA-G) Class I of low polymorphism and restricted tissue distribution that displays tolerogenic functions. In heart transplantation and in combined liver/renal allograft ...