Buscar
Mostrando ítems 21-30 de 34
Autoimmune orchitis and autoimmune oophoritis
(Academic Press Inc Elsevier Science, 2019)
Experimental studies predict a frequent occurrence of human gonadal autoimmunity. In spontaneous multi-organ models of autoimmune diseases, the testis and ovary are frequent targets. Although progress in clinical research ...
Inflammation and Spermatogenesis
(CRC Press - Taylor & Francis Group, 2018)
The testis is an immunologically privileged site with a unique immunosuppressor microenvironment able to tolerate haploid germ cell antigens that appear at puberty and to easily accept tissue grafts. However, this ...
Cytokines and chemokines in testicular inflammation: A brief review
(Wiley-liss, Div John Wiley & Sons Inc, 2009-08)
A wide spectrum of data in the literature shows the relevance of cytokines as paracrine regulators of spermatogenesis and steroidogenesis in the normal testis. In this brief review, we highlight the relevance of cytokines ...
CD4+ and CD8+ T cells producing Th1 and Th17 cytokines are involved in the pathogenesis of autoimmune orchitis
(BioScientifica, 2011-02)
Experimental autoimmune orchitis (EAO) is a useful model to study chronic testicular inflammation and infertility. EAO is characterized by severe damage of seminiferous tubules with germ cells that undergo apoptosis and ...
CD4+ Foxp3+ Regulatory T cells in autoimmune orchitis: phenotypic and functional characterization.
(Wiley, 2015-02)
Problem: The phenotype and function of regulatory T (Treg) cells in rats with experimental autoimmune orchitis (EAO) was evaluated. Method of study: Distribution of Treg cells in draining lymph nodes from the testis (TLN) ...
Expression of co-stimulatory molecules, chemokine receptors and proinflammatory cytokines in dendritic cells from normal and chronically inflamed rat testis
(Oxford University Press, 2007-12)
The presentation of self antigens by dendritic cells (DC) plays an important role in the initiation and maintenance of autoimmunity. In a model of experimental autoimmune orchitis (EAO), we have previously characterized ...
Targeting high mobility group box protein 1 ameliorates testicular inflammation in experimental autoimmune orchitis.
(Oxford University Press, 2015-02)
STUDY QUESTION: Does high mobility group box protein 1 (HMGB1) regulate inflammatory reactions in a rat model of experimental autoimmune orchitis (EAO)? SUMMARY ANSWER: HMGB1 appears to be involved in regulating inflammatory ...
Role of indoleamine 2,3-dioxygenase in testicular immune-privilege
(Natureresearch, 2019-10)
Male meiotic germ cell including the spermatozoa represent a great challenge to the immune system, as they appear long after the establishment of normal immune tolerance mechanisms. The capacity of the testes to tolerate ...
Estudio de las moléculas de adhesión celular y quemoquinas involucradas en el tráfico leucocitario en un cuadro de orquitis autoinmune experimentalExpression of cell adhesion molecules and chemokines involved in leucocyte traffic in rats undergoing autoimmune orchitis
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2006)