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Antimicrobial Photodynamic Therapy (APDT) Action Based on Nanostructured Photosensitizers
(2017-01-01)
Important features are linked to the concept of antimicrobial photodynamic therapy (APDT). One approach is the need of effective strategies to overcome bacterial resistance to antibiotics. In this context, APDT has emerged ...
Optimization of Antimicrobial Photodynamic Therapy in Biofilms by Inhibiting Efflux Pump
(2017-07-01)
Background: One of the main mechanisms of microbial resistance is given by efflux pumps, which reduce the effectiveness of antimicrobials by decreasing their intracellular concentration. Objective and methods: Considering ...
Rat tissue reaction and cytokine production induced by antimicrobial photodynamic therapy
(2017-06-01)
Background The antimicrobial photodynamic therapy (aPDT) inactivates the target cell via reactions among the photosensitizer (PS), Laser or Led and O2. The aim of this study was to evaluate the tissue reaction and cytokine ...
Antimicrobial photodynamic therapy against pathogenic bacterial suspensions and biofilms using chloro-aluminum phthalocyanine encapsulated in nanoemulsions
(2013)
Antimicrobial photodynamic therapy represents an alternative method of killing resistant pathogens. Efforts have been made to develop delivery systems for hydrophobic drugs to improve the photokilling. This study evaluated ...
Antimicrobial therapy in periodontitis: the use of systemic antimicrobials against the subgingival biofilm
(BLACKWELL, 2008-09)
Objectives: The aim was to answer three relevant questions: can systemic antimicrobials be efficacious if the biofilm is not disrupted? Can the type of debridement of the subgingival biofilm impact upon the clinical outcomes ...
Local adjunct effect of antimicrobial photodynamic therapy for the treatment of chronic periodontitis in type 2 diabetics: split-mouth double-blind randomized controlled clinical trial
(2016-11-01)
Diabetes has become a global epidemic. Its complications can have a significant impact on quality of life, longevity, and public health costs. The presence of diabetes might impair the prognosis of periodontal treatments ...
Consecutive treatments with photodynamic therapy and nystatin altered the expression of virulence and ergosterol biosynthesis genes of a fluconazole-resistant Candida albicans in vivo
(2021-03-01)
This investigation assessed the effect of five consecutive daily topical treatments of antimicrobial photodynamic therapy (aPDT), nystatin (NYS), and an association of treatments on a fluconazole-resistant strain of Candida ...