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MHC I presentation of Toxoplasma gondii immunodominant antigen does not require Sec22b and is regulated by antigen orientation at the vacuole membrane
(Wiley VCH Verlag, 2017-07)
The intracellular Toxoplasma gondii parasite replicates within a parasitophorous vacuole (PV). T. gondii secretes proteins that remain soluble in the PV space, are inserted into PV membranes or are exported beyond the PV ...
Effect of repetitiveness on the immunogenicity and antigenicity of Trypanosoma cruzi FRA protein
(Academic Press Inc Elsevier Science, 2011-03)
Repetitive proteins (RP) of Trypanosoma cruzi are highly present in the parasite and are strongly recognized by sera from Chagas' disease patients. Flagelar Repetitive Antigen (FRA), which is expressed in all steps of the ...
Mice hyperimmunized with syngeneic heart antigen present cellular and humoral responses against Trypanosoma Cruzi antigen
(Sociedade Brasileira de Medicina Tropical, 2019)
Galectin-8 Enhances T cell Response by Promotion of Antigen Internalization and Processing
(Cell Press, 2020-07)
Galectin-8 (Gal-8) is a mammalian lectin endowed with immunostimulatory ability. In the present work, we demonstrate that Gal-8-glycan interactions on the surface of antigen-presenting cells (APCs) promote antigen binding ...
Synchronous prostate and rectal cancer, a case report
(Urban and Partner, 2018-10)
The incidence of multiple primary neoplasms has been increasing over the years. Within this group, the coexistence of primary prostate cancer and primary colorectal cancer is one of the most frequent. The objective of this ...