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Development of microemulsions to topically deliver 5-aminolevulinic acid in photodynamic therapy
(ELSEVIER SCIENCE BV, 2010)
The aim of this study was to obtain and to characterize microemulsions containing 5-aminolevulinic acid (5-ALA) and to investigate the influence of these systems in drug skin permeation for further topical photodynamic ...
Improvement of an HPLC method to determine urinary δ-aminolevulinic acid
(Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, 2010)
OBJECTIVE: The purpose of this study was to evaluate and improve a high performance liquid chromatography (HPLC) methodology to determine urinary δ-aminolevulinic acid (ALA-U) with small volumes of sample. METHOD: The ...
The importance of protoporphyrin IX efflux for ALA-PDT dosimetry
(WILEY-V C H VERLAG GMBH, 2009)
One of the major advances in PDT is the use of 5-aminolevulinic acid (ALA) to induce the production of an enclogenous photosensitizer inside the cells using intracellular enzymatic pathways. ALA is the first intermediate ...
Assessment of ALA-induced PpIX production in porcine skin pretreated with microneedles
(2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim., 2015)