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Insights on the Structure of Amyloid Fibrils from Site-Directed Mutagenesis
(Bentham Science Publ LtdSharjahEmirados Árabes Unidos, 2009)
Folding of a dimeric β-barrel: Residual structure in the urea denatured state of the human papillomavirus E2 DNA binding domain
(Cambridge University Press, 2000-04)
The dimeric beta-barrel is a characteristic topology initially found in the transcriptional regulatory domain of the E2 DNA binding domain from papillomaviruses. We have previously described the kinetic folding mechanism ...
The E. coli thioredoxin folding mechanism: the key role of the C-terminal helix
(Elsevier Science, 2015-02)
In this work, the unfolding mechanism of oxidized Escherichia coli thioredoxin (EcTRX) was investigated experimentally and computationally. We characterized seven point mutants distributed along the C-terminal α-helix (CTH) ...
Collagen Type I, Collagen Type III, and Versican in Vocal Fold Lamina Propria
(AMER MEDICAL ASSOC, 2011)
Objective: To analyze the distributions of collagen type I, collagen type III, and versican in the lamina propria of the human vocal fold. Design: Cross-sectional analysis of cadaveric vocal folds of adult human larynges. ...
Quality Control in Glycoprotein Folding
(Wiley-VCH, 2005)
The concept of quality control of protein folding in the secretory pathway emerged in the late 1970s and early 1980s when it was noticed that not in all cases did insertion of proteins in the endoplasmic reticulum (ER) ...
Concentration and distribution of hyaluronic acid in human vocal folds
(Lippincott Williams & Wilkins, 2007-04-01)
Objective/Hypothesis. To evaluate the concentration and distribution of hyaluronic acid (HA) in human adult vocal folds. Study Design. Experimental study. Methods. Histologic samples of the anterior, middle, and posterior ...
The Endoplasmic Reticulum Glucosyltransferase Recognizes Nearly Native Glycoprotein Folding Intermediates
(American Society for Biochemistry and Molecular Biology, 2004-10)
The UDP-Glc:glycoprotein glucosyltransferase (GT), a key player in the endoplasmic reticulum (ER) quality control of glycoprotein folding, only glucosylates glycoproteins displaying non-native conformations. To determine ...
Effect of Internal Cavities on Folding Rates and Routes Revealed by Real-Time Pressure-Jump NMR Spectroscopy
(Amer Chemical SocWashingtonEUA, 2013)
Calreticulin and Calnexin as Chaperones in Glycoprotein Folding
(CRC Press - Taylor & Francis Group, 2009)
Protein folding efficiency is enhanced in vivo by an array of chaperones and folding-assisting enzymes that cover the entire protein folding pathway, from the exit of the polypeptide from the ribosome, its translocation ...