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Influência da empagliflosina na remodelação cardíaca induzida pela exposição à fumaça de cigarros
(Universidade Estadual Paulista (Unesp), 2021-03-22)
Introdução: A exposição à fumaça de cigarros aumenta o risco para doenças cardiovasculares, tais como hipertrofia e disfunção miocárdica, e entre outros problemas de saúde. A exposição a fumaça de cigarro também pode levar ...
Complicaciones macrovasculares de la diabetes: Rol de NFAT y proteínas afines como posibles blancos terapéuticos
(Udelar. FM, 2019)
La diabetes mellitus (DM) es una enfermedad crónica, con una alta incidencia mundial. Además de las complicaciones microvasculares que trae consigo la DM y que llevan al desarrollo de retinopatía, nefropatía y neuropatía; ...
Sizing up entanglement in mutually unbiased bases with Fisher information
(2013)
We present a single-shot method for phase recovery based on the transport of irradiance equation (TIE). The system utilizes a beamsplitter and mirrors to achieve two simultaneous (laterally separated) images with different ...
Dopamine Receptor D1 Contributes to Cocaine Epigenetic Reprogramming of Histone Modifications in Male Germ Cells
(Frontiers Media S.A., 2020-04-03)
Paternal environmental perturbations, including cocaine intake, can affect the development and behavior of the offspring through epigenetic inheritance. However, the mechanism by which cocaine alters the male germ cells ...
Efeito da ingestão de extrato de chá verde rico em epigalocatequina-3-galato sobre reguladores metabólicos hepáticos de camundongos obesos induzidos por dieta hiperlipídica
(Universidade Federal de São Paulo (UNIFESP), 2015-04-30)
Introdução: A esteatose hepática tem sido considerada a manifestação hepática da obesidade. Diversos estudos propõem efeitos benéficos das catequinas do chá verde, mas não está clara a influência da suplementação de extrato ...
RAC3 more than a nuclear receptor coactivator: A key inhibitor of senescence that is down-regulated in aging
(Nature Publishing Group, 2015-10)
Receptor-associated coactivator 3 (RAC3) is a nuclear receptor coactivator usually overexpressed in tumors that exerts oncogenicfunctions in the cytoplasm and the nucleus. Although as part of its oncogenic actions it was ...
Molecular mechanisms and signaling pathways involved in Sertoli cell proliferation
(Frontiers Media, 2019-04)
Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited number of germ cells, the final ...
Resveratrol exerts anti-oxidant and anti-inflammatory actions and prevents oxaliplatin induced mechanical and thermal allodynia
(Elsevier Science, 2020-12)
Chemotherapy-induced peripheral neuropathic pain (CIPNP) is a frequent and devastating side effect of cancer therapy. No preventive strategies are currently available. We investigated the use of resveratrol (RESV) in the ...