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Potencial terapêutico cardíaco das células tronco mesenquimais precursoras de medula óssea Cd271+
(Universidade Federal de São Paulo (UNIFESP), 2018-03-29)
MSCs are a particularly promising bone marrow-derived cell for cardiac regenerative therapy because of their availability, immunologic properties, and record of safety and efficacy. Several studies have confirmed the ...
Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes
(Nature Publishing Group, 2013-01)
Cell-fate control gene therapy (CFCGT)-based strategies can augment existing gene therapy and cell transplantation approaches by providing a safety element in the event of deleterious outcomes. Previously, we described a ...
Human umbilical cord perivascular cells exhibit enhanced cardiomyocyte reprogramming and cardiac function after experimental acute myocardial infarction
(Sage Publications, 2013-09)
We were interested in evaluating the ability of the mesenchymal stromal cell (MSC) population, human umbilical cord perivascular cells (HUCPVCs), to undergo cardiomyocyte reprogramming in an established co-culture system ...
Site Specific Knock-In Genome Editing in Human HSCs Using Baboon Envelope gp Pseudotypedviral Derived “Nanoblades” Loaded with Cas9/sgRNA Combined with Donor Encoding AAV-6
(Elsevier, 2019)
Programmable nucleases have enabled rapid and accessible genome engineering in eukaryotic cells and living organisms. Here, we have designed ?Nanoblades?, a new technology that will deliver a genomic cleaving agent into ...
Interaction between FGFR-2, STAT5, and progesterone receptors in breast cancer
(American Association for Cancer Research, 2011-05)
Fibroblast growth factor (FGF) receptor 2 (FGFR-2) polymorphisms have been associated with an increase in estrogen receptor and progesterone receptor (PR)-positive breast cancer risk; however, a clear mechanistic association ...
Genomic Profiling Of Type-1 Adult Diabetic And Aged Normoglycemic Mouse Liver
(BioMed Central Ltd., 2014)