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Mostrando ítems 11-20 de 174
Molecular Design, Synthesis and Evaluation of 2,3-Diarylquinoxalines as Estrogen Receptor Ligands
(Bentham Science Publ Ltd, 2015-01-01)
Selective Estrogen Receptor Modulators (SERMs) are characteristically capable of being antagonist and agonist of estrogen receptors and, therefore, they can inhibit or stimulate estrogen production in different tissues. ...
Can maternal exposure to tamoxifen compromise sperm and behavioural parameters of male rat offspring?
(2022-03-01)
Tamoxifen, a selective non-steroidal estrogen receptor modulator, is the standard adjuvant endocrine treatment for breast cancer. Since information on the risk of using tamoxifen during pregnancy is still scarce, this study ...
Effects of Ginkgo biloba on chemically-induced mammary tumors in rats receiving tamoxifen
(2013-05-01)
Background: Ginkgo biloba extract (GbE) is used extensively by breast cancer patients undergoing treatment with Tamoxifen (TAM). Thus, the present study investigated the effects of GbE in female Sprague-Dawley (SD) rats ...
Effects of Ginkgo biloba on chemically-induced mammary tumors in rats receiving tamoxifen
(2013-05-01)
Background: Ginkgo biloba extract (GbE) is used extensively by breast cancer patients undergoing treatment with Tamoxifen (TAM). Thus, the present study investigated the effects of GbE in female Sprague-Dawley (SD) rats ...
Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells
(2019-01)
Synthetic selective modulators of the estrogen receptors (SERMs) have shown to protect neurons and glial cells against toxic insults. Among the most relevant beneficial effects attributed to these compounds are the regulation ...
Assessment of micronucleus frequency in the peripheral blood of female rats in persistent estrus treated with selective estrogen receptor modulators
(WILEY-BLACKWELLMALDEN, 2012-01)
The aim of this study was to evaluate micronucleus (MN) frequency in polychromatic erythrocytes (PCE) of female rats in persistent estrus (a model developed to mimic polycystic ovary syndrome) treated with selective estrogen ...