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Mostrando ítems 11-17 de 17
Isoform Selectivity of Adenylyl Cyclase Inhibitors: Characterization of Known and Novel Compounds
(American Society For Pharmacology And Experimental Therapeutics, 2013-11)
Nine membrane-bound adenylyl cyclase (AC) isoforms catalyze the production of the second messenger cyclic AMP (cAMP) in response to various stimuli. Reduction of AC activity has well documented benefits, including benefits ...
Non-mutagenic Ru(ii) complexes: Cytotoxicity, topoisomerase IB inhibition, DNA and HSA binding
(2019-01-01)
Herein we discuss five ruthenium(ii) complexes with good cytotoxicity against cancer cells. These complexes are named [Ru(tzdt)(bipy)(dppb)]PF6 (1), [Ru(mmi)(bipy)(dppb)]PF6 (2), [Ru(dmp)(bipy)(dppb)]PF6 (3), [Ru(mpca)(b ...
Quinazoline-tethered hydrazone: A versatile scaffold toward dual anti-TB and EGFR inhibition activities in NSCLC
(Wiley VCH Verlag, 2021-09)
Globally, lung cancer and tuberculosis are considered to be very serious and complex diseases. Evidence suggests that chronic infection with tuberculosis (TB) can often lead to lung tumors; therefore, developing drugs that ...
Comparison of the Effectiveness of Halofuginone Lactate and Paromomycin in the Treatment of Calves Naturally Infected with Cryptosporidium parvum
(Universidade Federal do Rio Grande do Sul, 2018)
Citotoxidade e mecanismo de ação de complexos Ru(II)/2-mercapto-4(3H)quinazolinona em células de câncer de pele
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2023-02-28)
Ruthenium biphosphynic complexes combined with mercapto ligands have shown low IC50 values and good selectivity indexes (SI) in different tumor lines studied, which has motivated the development of ruthenium compounds with ...
Evaluación de los fungicidas proquinazid y tetraconazole en el control de oídio (Erysiphe necator) en vid vinífera (Vitis vinifera L.)
(Universidad de Talca (Chile). Escuela de Agronomía., 2016)