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Hydrogen activatión by carbene systems and proton transfer reactións. A reactión electronic flux analysis
(2013)
This Thesis was performed on the theoretical analysis of reaction mechanisms in a variety of chemical processes, ranging from the study of the biologically relevant chemical reactions to more chemically-oriented reactions. ...
Regulation of FKBP51 and FKBP52 functions by post-translational modifications
(Portland Press, 2019-10)
FKBP51 and FKBP52 are two iconic members of the family of peptidyl-prolyl-(cis/trans)-isomerases (EC: 5.2.1.8), which comprises proteins that catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds in unfolded ...
Improved Immuno-Detection of a Low-Abundance Cyclophilin Allows the Confirmation of its Expression in a Protozoan Parasite
(Omics International, 2015-10)
Protein samples can be challenging to analyze due to the presence of high-abundance proteins masking low abundance proteins of interest, such as biomarkers and novel physiological mediators. Cyclophilins are chaperones ...
Rational design of PIN1 inhibitors for cancer treatment based on conformational diversity analysis and docking based virtual screening
(Adenine Press, 2021-01)
The parvulin PIN1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1), is the only enzyme capable of isomerizing prolines of phospho-Serine/Threonine-Proline motifs. PIN1 binds to a subset of proteins and plays an ...
Estudio teórico-experimental de la síntesis y propiedades físico-químicas de derivados de N-bencil-1-(2-furanil) Metanamina
(Universidad Pedagógica y Tecnológica de ColombiaFacultad de Ciencias, Escuela de Posgrados. Maestría en Química, 2018)
Theoretical and experimental study of the reaction system and DA cycloaddition products of N-benzyl-1-(furan-2-yl)methanamine (1a), and N-benzyl-N-(furan-2-ylmethyl)acetamide (1b) was developed using maleic anhydride (AnM) ...